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  • Ericsson, MalinKarolinska Institutet (författare)

Childhood social class and cognitive aging in the Swedish Adoption/Twin Study of Aging

  • Artikel/kapitelEngelska2017

Förlag, utgivningsår, omfång ...

  • 2017-06-19
  • National Academy of Sciences,2017
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:his-21866
  • https://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-21866URI
  • https://doi.org/10.1073/pnas.1620603114DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-37239URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:136144378URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-145995URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • SATSA was supported by NIH Grants R01 AG04563 and R01 AG10175, the MacArthur Foundation Research Network on Successful Aging, the Swedish Research Council for Working Life and Social Research (FAS; Grants 97:0147:1B, 2009-0795), and the Swedish Research Council Grants (825-2007-7460 and 825-2009-6141). This work was supported by NIH Grants R01 AG037985 and R56 AG037985, the Swedish Research Council Grant (2013-08689), and FORTE (the Swedish Research Council for Health, Working Life, and Welfare; Grant 2013-02292).
  • In this report we analyzed genetically informative data to investigate within-person change and between-person differences in late-life cognitive abilities as a function of childhood social class. We used data from nine testing occasions spanning 28 y in the Swedish Adoption/Twin Study of Aging and parental social class based on the Swedish socioeconomic index. Cognitive ability included a general factor and the four domains of verbal, fluid, memory, and perceptual speed. Latent growth curve models of the longitudinal data tested whether level and change in cognitive performance differed as a function of childhood social class. Between-within twin-pair analyses were performed on twins reared apart to assess familial confounding. Childhood social class was significantly associated with mean-level cognitive performance at age 65 y, but not with rate of cognitive change. The association decreased in magnitude but remained significant after adjustments for level of education and the degree to which the rearing family was supportive toward education. A between-pair effect of childhood social class was significant in all cognitive domains, whereas within-pair estimates were attenuated, indicating genetic confounding. Thus, childhood social class is important for cognitive performance in adulthood on a population level, but the association is largely attributable to genetic influences.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Lundholm, CeciliaKarolinska Institutet (författare)
  • Fors, StefanStockholms universitet,Karolinska Institutet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)(Swepub:su)stfo7271 (författare)
  • Dahl Aslan, Anna K.,1975-Karolinska Institutet,Jönköping University,HHJ, Institutet för gerontologi,HHJ. ARN-J (Aging Research Network - Jönköping),Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden ; Institute for Gerontology, School of Health and Welfare, Jönköping University, Sweden(Swepub:hj)daan (författare)
  • Zavala, CatalinaDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden ; Department of Psychology, University of Southern California, Los Angeles, United States (författare)
  • Reynolds, Chandra A.Department of Psychology, University of California, Riverside, United States (författare)
  • Pedersen, Nancy L.Karolinska Institutet (författare)
  • Karolinska InstitutetCentrum för forskning om äldre och åldrande (ARC), (tills m KI) (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Proceedings of the National Academy of Sciences of the United States of America: National Academy of Sciences114:27, s. 7001-70060027-84241091-6490

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