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Associations of job...
Associations of job strain and lifestyle risk factors with risk of coronary artery disease : a meta-analysis of individual participant data
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- Kivimäki, Mika (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Nyberg, Solja (author)
- Centre of Expertise for the Development of Work and Organizations, Finnish Institute of Occupational Health, Helsinki, Finland
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- Fransson, Eleonor (author)
- Stockholms universitet,Karolinska Institutet,Jönköping University,HHJ, Avdelningen för naturvetenskap och biomedicin,HHJ. ADULT,School of Health Sciences, Jönköping University, Jönköping, Sweden,Stressforskningsinstitutet
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- Heikkilä, Katriina (author)
- Centre of Expertise for the Development of Work and Organizations, Finnish Institute of Occupational Health, Helsinki, Finland
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- Alfredsson, Lars (author)
- Karolinska Institutet
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- Casini, Annalisa (author)
- School of Public Health, Université Libre de Bruxelles, Brussels, Belgium
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- Clays, Els (author)
- Department of Public Health, Ghent University, Ghent, Belgium
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- DeBacquer, Dirk (author)
- Department of Public Health, Ghent University, Ghent, Belgium
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- Dragano, Nico (author)
- Department of Medical Sociology, University of Düsseldorf, Düsseldorf, Germany
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- Ferrie, Jane (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Goldberg, Marcel (author)
- Inserm U1018, Institut National de la Santé et de la Recherche Médicale, Villejuif Cedex, France
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- Hamer, Mark (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Westerholm, Peter J. M. (author)
- Uppsala universitet,Arbets- och miljömedicin
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- Karasek, Robert (author)
- Department of Work Environment, University of Massachusetts, Lowell, MA, United States
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- Kittel, France (author)
- School of Public Health, Université Libre de Bruxelles, Brussels, Belgium
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- Knutsson, Anders (author)
- Mittuniversitetet,Avdelningen för hälsovetenskap
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- Koskenvuo, Markku (author)
- Department of Public Health, University of Helsinki, Helsinki, Finland
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- Nordin, Maria (author)
- Umeå universitet,Institutionen för psykologi,Department of Psychology, Umeå University, Umeå, Sweden
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- Oksanen, Tuula (author)
- Centre of Expertise for the Development of Work and Organizations, Finnish Institute of Occupational Health, Helsinki, Finland
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- Pentti, Jaana (author)
- Centre of Expertise for the Development of Work and Organizations, Finnish Institute of Occupational Health, Helsinki, Finland
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- Rugulies, Reiner (author)
- National Research Centre for the Working Environment, Copenhagen, Denmark
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- Salo, Paula (author)
- Centre of Expertise for the Development of Work and Organizations, Finnish Institute of Occupational Health, Helsinki, Finland
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- Siegrist, Johannes (author)
- Department of Medical Sociology, University of Düsseldorf, Düsseldorf, Germany
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- Suominen, Sakari (author)
- Department of Public Health, University of Turku, Turku, Finland
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- Theorell, Töres (author)
- Stockholms universitet,Karolinska Institutet,Stressforskningsinstitutet
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- Vahtera, Jussi (author)
- Stockholms universitet,Stressforskningsinstitutet,University of Turku, Finland
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- Virtanen, Marianna (author)
- Centre of Expertise for the Development of Work and Organizations, Finnish Institute of Occupational Health, Helsinki, Finland
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Westerholm, Peter (author)
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- Westerlund, Hugo (author)
- Stockholms universitet,Karolinska Institutet,Stressforskningsinstitutet
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- Zins, Marie (author)
- Inserm U1018, Institut National de la Santé et de la Recherche Médicale, Villejuif Cedex, France
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- Steptoe, Andrew (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Singh-Manoux, Archana (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Batty, David (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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(creator_code:org_t)
- 2013-05-13
- 2013
- English.
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In: CMJA. Canadian Medical Association Journal. Onlineutg. Med tittel. - : CMA Joule Inc.. - 0820-3946 .- 1488-2329. ; 185:9, s. 763-769
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https://miun.diva-po... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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https://urn.kb.se/re...
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Abstract
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- Background: It is unclear whether a healthy lifestyle mitigates the adverse effects of job strain on coronary artery disease. We examined the associations of job strain and lifestyle risk factors with the risk of coronary artery disease.Methods: We pooled individual-level data from 7 cohort studies comprising 102 128 men and women who were free of existing coronary artery disease at baseline (1985–2000). Questionnaires were used to measure job strain (yes v. no) and 4 lifestyle risk factors: current smoking, physical inactivity, heavy drinking and obesity. We grouped participants into 3 lifestyle categories: healthy (no lifestyle risk factors), moderately unhealthy (1 risk factor) and unhealthy (2–4 risk factors). The primary outcome was incident coronary artery disease (defined as first nonfatal myocardial infarction or cardiac-related death).Results: There were 1086 incident events in 743 948 person-years at risk during a mean follow-up of 7.3 years. The risk of coronary artery disease among people who had an unhealthy lifestyle compared with those who had a healthy lifestyle (hazard ratio [HR] 2.55, 95% confidence interval [CI] 2.18–2.98; population attributable risk 26.4%) was higher than the risk among participants who had job strain compared with those who had no job strain (HR 1.25, 95% CI 1.06–1.47; population attributable risk 3.8%). The 10-year incidence of coronary artery disease among participants with job strain and a healthy lifestyle (14.7 per 1000) was 53% lower than the incidence among those with job strain and an unhealthy lifestyle (31.2 per 1000).Interpretation: The risk of coronary artery disease was highest among participants who reported job strain and an unhealthy lifestyle; those with job strain and a healthy lifestyle had half the rate of disease. A healthy lifestyle may substantially reduce disease risk among people with job strain.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Kivimäki, Mika
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Nyberg, Solja
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Fransson, Eleono ...
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Heikkilä, Katrii ...
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Alfredsson, Lars
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Casini, Annalisa
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show more...
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Clays, Els
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DeBacquer, Dirk
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Dragano, Nico
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Ferrie, Jane
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Goldberg, Marcel
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Hamer, Mark
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Westerholm, Pete ...
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Karasek, Robert
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Kittel, France
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Knutsson, Anders
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Koskenvuo, Markk ...
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Nordin, Maria
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Oksanen, Tuula
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Pentti, Jaana
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Rugulies, Reiner
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Salo, Paula
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Siegrist, Johann ...
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Suominen, Sakari
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Theorell, Töres
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Vahtera, Jussi
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Virtanen, Marian ...
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Westerholm, Pete ...
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Westerlund, Hugo
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Zins, Marie
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Steptoe, Andrew
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Singh-Manoux, Ar ...
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Batty, David
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Jönköping University
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Umeå University
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Mid Sweden University
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Karolinska Institutet
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Stockholm University
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Uppsala University