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Cortical reorganiza...
Cortical reorganization following injury early in life
- Artikel/kapitelEngelska2016
Förlag, utgivningsår, omfång ...
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Hindawi Publishing Corporation,2016
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:hj-37447
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https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-37447URI
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https://doi.org/10.1155/2016/8615872DOI
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Språk:engelska
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Sammanfattning på:engelska
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Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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The brain has a remarkable capacity for reorganization following injury, especially during the first years of life. Knowledge of structural reorganization and its consequences following perinatal injury is sparse. Here we studied changes in brain tissue volume, morphology, perfusion, and integrity in children with hemiplegia compared to typically developing children, using MRI. Children with hemiplegia demonstrated reduced total cerebral volume, with increased cerebrospinal fluid (CSF) and reduced total white matter volumes, with no differences in total gray matter volume, compared to typically developing children. An increase in cortical thickness at the hemisphere contralateral to the lesion (CLH) was detected in motor and language areas, which may reflect compensation for the gray matter loss in the lesion area or retention of ipsilateral pathways. In addition, reduced cortical thickness, perfusion, and surface area were detected in limbic areas. Increased CSF volume and precentral cortical thickness and reduced white matter volume were correlated with worse motor performance. Brain reorganization of the gray matter within the CLH, while not necessarily indicating better outcome, is suggested as a response to neuronal deficits following injury early in life.
Ämnesord och genrebeteckningar
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MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
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MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
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adolescent
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Article
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brain cortex lesion
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brain function
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brain injury
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brain perfusion
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brain size
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brain tissue
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cerebrospinal fluid
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child
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clinical article
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cortical thickness (brain)
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female
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gray matter
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hemiplegia
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human
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male
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morphology
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neuroimaging
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nuclear magnetic resonance imaging
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perinatal period
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white matter
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age
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brain cortex
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complication
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diagnostic imaging
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organ size
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pathophysiology
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physiology
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trends
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Age Factors
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Brain Injuries
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Cerebral Cortex
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Humans
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Magnetic Resonance Imaging
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Shiran, S. I.
(författare)
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Weinstein, M.
(författare)
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Myers, V.
(författare)
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Tarrasch, R.
(författare)
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Schertz, M.
(författare)
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Fattal-Valevski, A.
(författare)
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Miller, E.
(författare)
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Gordon, A. M.
(författare)
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Green, DidoDepartment Occupational Therapy, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel(Swepub:hj)gredid
(författare)
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Ben Bashat, D.
(författare)
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Department Occupational Therapy, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Neural Plasticity: Hindawi Publishing Corporation2090-59041687-5443
Internetlänk
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Till lärosätets databas
- Av författaren/redakt...
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Artzi, M.
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Shiran, S. I.
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Weinstein, M.
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Myers, V.
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Tarrasch, R.
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Schertz, M.
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visa fler...
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Fattal-Valevski, ...
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Miller, E.
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Gordon, A. M.
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Green, Dido
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Ben Bashat, D.
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Neurologi
- Artiklar i publikationen
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Neural Plasticit ...
- Av lärosätet
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Jönköping University