Search: WFRF:(Karlsson C.)
> (2010-2014) >
Common breast cance...
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers : Implications for risk prediction
-
- Antoniou, A. C. (author)
- Center for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom,University Turin, Department Genet Biol and Biochem, Turin, Italy,IRCCS, Ist Oncol Veneto, Immunol and Mol Oncol Unit, Padua, Italy
-
- Beesley, J. (author)
- Queensland Institute of Medical Research, Brisbane, Australia
-
- McGuffog, L. (author)
- University Cambridge, Centre Canc Genet Epidemiol, Department Publ Hlth and Primary Care, Cambridge, England,Mayo Clin, Department Med Genet, Rochester, MN USA
-
show more...
-
- Sinilnikova, O. M. (author)
- Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Centre Hospitalier Universitaire de Lyon/Centre Léon Bérard, Lyon, France,IRCCS, Ist Oncol Veneto, Immunol and Mol Oncol Unit, Padua, Italy
-
- Healey, S. (author)
- Queensland Institute Med Research, Brisbane, Qld, Australia
-
- Neuhausen, S. L. (author)
- Beckman Research Institute City Hope, Department Populat Science, Duarte, CA USA,Aalborg Hospital, Department Clin Genet, Aalborg, Denmark,Roswell Pk Canc Institute, Department Canc Prevent and Control, Buffalo, NY 14263 USA
-
- Ding, Y. C. (author)
- Beckman Research Institute City Hope, Department Populat Science, Duarte, CA USA,Dana Farber Canc Institute, Boston, MA 02115 USA
-
- Rebbeck, T. R. (author)
- University Penn, Sch Med, Abramson Canc Centre, Philadelphia, PA 19104 USA
-
- Weitzel, J. N. (author)
- City Hope Natl Med Centre, Duarte, CA 91010 USA
-
- Lynch, H. T. (author)
- Creighton University, Omaha, NE 68178 USA,Pomeranian Med University, Int Hereditary Canc Centre, Department Genet and Pathol, Szczecin, Poland,Queensland Institute Med Research, Brisbane, Qld, Australia
-
- Isaacs, C. (author)
- Mayo Clin, Coll Med, Department Lab Med and Pathol, Rochester, MN USA
-
- Ganz, P. A. (author)
- University Calif Los Angeles, Jonsson Comprehens Canc Centre, Los Angeles, CA 90024 USA,Fdn IRCCS Ist Nazl Tumori INT, Unit Genet Susceptibil Canc, Department Expt Oncol and Mol Med, Milan, Italy
-
- Tomlinson, G. (author)
- University Texas Hlth Science Centre San Antonio, San Antonio, TX 78229 USA
-
- Olopade, O. I. (author)
- University Chicago, Med Centre, Chicago, IL 60637 USA
-
- Couch, F. J. (author)
- Mayo Clin, Department Lab Med and Pathol, Rochester, MN USA
-
- Wang, X. (author)
- Mayo Clin, Department Lab Med and Pathol, Rochester, MN USA
-
- Nordling, Margareta, 1962 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics
-
- Pankratz, V. S. (author)
- Mayo Clin, Department Hlth Science Research, Rochester, MN USA
-
- Radice, P. (author)
- Fdn IRCCS Ist Nazl Tumori INT, Unit Genet Susceptibil Canc, Department Expt Oncol and Mol Med, Milan, Italy
-
- Manoukian, S. (author)
- Fdn IRCCS Ist Nazl Tumori INT, Unit Med Genet, Department Prevent and Predict Med, Milan, Italy
-
- Peissel, B. (author)
- Fdn IRCCS Ist Nazl Tumori INT, Unit Med Genet, Department Prevent and Predict Med, Milan, Italy
-
- Zaffaroni, D. (author)
- Fdn IRCCS Ist Nazl Tumori INT, Unit Med Genet, Department Prevent and Predict Med, Milan, Italy
-
- Stenmark-Askmalm, Marie (author)
- Östergötlands Läns Landsting,Linköpings universitet,Lund University,Lunds universitet,Avdelningen för klinisk genetik,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Clinical Genetics,Department of Laboratory Medicine,Faculty of Medicine,Onkologi,Hälsouniversitetet,Klinisk patologi och klinisk genetik
-
- Viel, A. (author)
- IRCCS, CRO, Div Expt Oncol 1, Aviano, PN, Italy
-
- Allavena, A. (author)
- Karolinska Institutet,University Hospital, Department Pathol, Reykjavik, Iceland
-
Dall'Olio, V. (author)
-
Peterlongo, P. (author)
-
Szabo, C. I. (author)
-
- Zikan, M. (author)
- Charles University Prague, Fac Med 1, Department Biochem and Expt Oncol, Prague, Czech Republic
-
- Claes, K. (author)
- Ghent University Hospital, Centre Med Genet, B-9000 Ghent, Belgium
-
- Poppe, B. (author)
- Ghent University Hospital, Centre Med Genet, B-9000 Ghent, Belgium
-
- Foretova, L. (author)
- Masaryk Mem Canc Institute, Department Canc Epidemiol and Genet, Brno, Czech Republic
-
- Mai, P. L. (author)
- US Natl Canc Institute, Clin Genet Branch, Rockville, MD USA
-
- Greene, M. H. (author)
- US Natl Canc Institute, Clin Genet Branch, Rockville, MD USA
-
- Rennert, G. (author)
- Technion Israel Institute Technology, Carmel Med Centre, Haifa, Israel
-
- Lejbkowicz, F. (author)
- Technion Israel Institute Technology, Carmel Med Centre, Haifa, Israel
-
- Glendon, G. (author)
- OCGN, Toronto, ON, Canada
-
- Ozcelik, H. (author)
- Mt Sinai Hospital, Fred A Litwin Centre Canc Genet, Samuel Lunenfeld Research Institute, New York, NY 10029 USA,University Copenhagen, Rigshosp, Department Clin Biochem, DK-2100 Copenhagen, Denmark
-
- Andrulis, I. L. (author)
- OCGN, Toronto, ON, Canada
-
- Thomassen, M. (author)
- Odense University Hospital, Department Clin Genet, DK-5000 Odense, Denmark
-
- Gerdes, A. -M (author)
- Rigshosp, Department Clin Genet, Odense, Denmark,Dana Farber Canc Institute, Boston, MA 02115 USA,Tech University Munich, Klinikum Rechts Isar, Department Obstet and Gynaecol, Div Tumor Genet, D-8000 Munich, Germany
-
Sunde, L. (author)
-
- Cruger, D. (author)
- Vejle Hospital, Department Clin Genet, Velje, Denmark
-
- Jensen, U. B. (author)
- Aarhus University Hospital, Department Clin Genet, DK-8000 Aarhus, Denmark
-
- Caligo, M. (author)
- University Pisa, Div Surg Mol and Ultrastruct Pathol, Department Oncol, Pisa, Italy
-
- Friedman, E. (author)
- Sheba Med Centre, Susanne Levy Gertner Oncogenet Unit, Tel Hashomer, Israel,University Chicago, Med Centre, Chicago, IL 60637 USA
-
- Kaufman, B. (author)
- Sheba Med Centre, Institute Oncol, Tel Hashomer, Israel
-
- Laitman, Y. (author)
- Sheba Med Centre, Susanne Levy Gertner Oncogenet Unit, Tel Hashomer, Israel
-
- Milgrom, R. (author)
- Sheba Med Centre, Susanne Levy Gertner Oncogenet Unit, Tel Hashomer, Israel
-
- Dubrovsky, M. (author)
- Sheba Med Centre, Susanne Levy Gertner Oncogenet Unit, Tel Hashomer, Israel
-
- Cohen, S. (author)
- Sheba Med Centre, Susanne Levy Gertner Oncogenet Unit, Tel Hashomer, Israel
-
- Borg, A. (author)
- Lund University, Department Oncol, Lund, Sweden,Queensland Institute Med Research, Brisbane, Qld, Australia
-
- Jernström, Helena (author)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University, Department Oncol, Lund, Sweden
-
- Lindblom, A. (author)
- Karolinska Institute, Department Mol Med and Surg, Stockholm, Sweden
-
- Rantala, J. (author)
- Karolinska Institutet,Karolinska Institute, Department Mol Med and Surg, Stockholm, Sweden
-
Stenmark-Askmalm, M. (author)
-
- Melin, Beatrice (author)
- Umeå universitet,Onkologi,Umea University, Department Radiat Science, Umea, Sweden
-
- Nathanson, K. (author)
- University Penn, Philadelphia, PA 19104 USA
-
- Domchek, S. (author)
- University Penn, Philadelphia, PA 19104 USA
-
- Jakubowska, A. (author)
- Pomeranian Med University, Int Hereditary Canc Centre, Department Genet and Pathol, Szczecin, Poland,Leiden University, Med Centre, Department Clin Genet, Leiden, Netherlands
-
- Lubinski, J. (author)
- Pomeranian Med University, Int Hereditary Canc Centre, Department Genet and Pathol, Szczecin, Poland,University Melbourne, Melbourne, Vic, Australia
-
Huzarski, T. (author)
-
- Osorio, A. (author)
- Spanish Natl Canc Research Centre, Human Genet Grp, Human Canc Genet Programme, Madrid, Spain
-
- Lasa, A. (author)
- Hospital Santa Creu and Sant Pau, Genet Serv, Barcelona, Spain
-
- Durán, M. (author)
- University Valladolid, Institute Biol and Mol Genet, IBGM UVA, Valladolid, Spain
-
- Tejada, M. -I (author)
- Cruces Hospital Barakaldo, Mol Genet Lab, Department Biochem, Bizkaia, Spain
-
- Godino, J. (author)
- University Lozano Blesa, Hospital Clin, Oncol Serv, Zaragoza, Spain
-
- Benitez, J. (author)
- Spanish Natl Canc Research Centre, Human Canc Genet Programme, Genotyping Unit, Madrid, Spain
-
- Hamann, U. (author)
- Deutsch Krebsforschungszentrum, Mol Genet Breast Canc, D-6900 Heidelberg, Germany
-
- Kriege, M. (author)
- Daniel Denhoed Canc Centre, Erasmus MC, Department Med Oncol, Family Canc Clin, Rotterdam, Netherlands
-
- Hoogerbrugge, N. (author)
- Radboud University Nijmegen, Nijmegen Med Centre, Hereditary Canc Clin, NL-6525 ED Nijmegen, Netherlands
-
- Van Der Luijt, R. B. (author)
- University Med Centre Utrecht, Department Med Genet, Utrecht, Netherlands
-
- Van Asperen, C. J. (author)
- Sheffield Childrens Hospital, Sheffield Clin Genet Serv, Sheffield, S Yorkshire, England
-
- Devilee, P. (author)
- Leiden University, Department Human Genet, Med Centre, Department Pathol, NL-2300 RA Leiden, Netherlands
-
- Meijers-Heijboer, E. J. (author)
- Vrije University Amsterdam Med Centre, Department Clin Genet, Amsterdam, Netherlands,Canc Prevent Institute Calif, Fremont, CA USA
-
- Blok, M. J. (author)
- University Med Centre, Department Genet and Cell Biol, Maastricht, Netherlands
-
- Aalfs, C. M. (author)
- University Amsterdam, Acad Med Centre, Department Clin Genet, NL-1105 AZ Amsterdam, Netherlands,University Cambridge, Centre Canc Genet Epidemiol, Department Publ Hlth and Primary Care, Cambridge, England
-
- Hogervorst, F. (author)
- Netherlands Canc Institute, Family Canc Clin, Amsterdam, Netherlands
-
- Rookus, M. (author)
- Netherlands Canc Institute, Department Epidemiol, Amsterdam, Netherlands
-
Cook, M. (author)
-
- Oliver, C. (author)
- University Cambridge, Centre Canc Genet Epidemiol, Department Publ Hlth and Primary Care, Cambridge, England
-
- Frost, D. (author)
- University Cambridge, Centre Canc Genet Epidemiol, Department Publ Hlth and Primary Care, Cambridge, England
-
- Conroy, D. (author)
- University Cambridge, Department Oncol, Cambridge, England
-
- Evans, D. G. (author)
- Cent Manchester University Hospital NHS Fdn Trust, Manchester Acad Hlth Science Centre, Manchester, Lancs, England,University Utah, Department Dermatol, Salt Lake City, UT USA,Hannover Med Sch, Institute Cell and Mol Pathol, D-3000 Hannover, Germany
-
- Lalloo, F. (author)
- Cent Manchester University Hospital NHS Fdn Trust, Manchester Acad Hlth Science Centre, Manchester, Lancs, England
-
- Pichert, G. (author)
- Guys and St Thomas NHS Fdn Trust, London, England
-
- Davidson, R. (author)
- Ferguson Smith Centre Clin Genet, Glasgow, Lanark, Scotland
-
- Cole, T. (author)
- Birmingham Womens Hospital Healthcare NHS Trust, W Midlands Reg Genet Serv, Birmingham, W Midlands, England
-
Cook, J. (author)
-
- Paterson, J. (author)
- Addenbrookes Hospital, Department Clin Genet, E Anglian Reg Genet Serv, Cambridge, England
-
- Hodgson, S. (author)
- University London, Department Clin Genet, St Georges Hospital, London, England
-
- Morrison, P. J. (author)
- Belfast City Hospital, Northern Ireland Reg Genet Centre, Belfast BT9 7AD, Antrim, North Ireland
-
- Porteous, M. E. (author)
- Western Gen Hospital, SE Scotland Reg Genet Serv, Edinburgh EH4 2XU, Midlothian, Scotland
-
- Walker, L. (author)
- Churchill Hospital, Oxford Reg Genet Serv, Oxford OX3 7LJ, England
-
- Kennedy, M. J. (author)
- St James Hospital, Canc Genet Program, Hope Directorate, Dublin, Ireland
-
- Dorkins, H. (author)
- Kennedy Galton Centre, NW Thames Reg Genet Serv, Harrow, Middx, England
-
- Peock, S. (author)
- University Cambridge, Centre Canc Genet Epidemiol, Department Publ Hlth and Primary Care, Cambridge, England
-
- Godwin, A. K. (author)
- Fox Chase Canc Centre, Department Med Oncol, Womens Canc Program, Philadelphia, PA 19111 USA,Tech University Dresden, Department Obstet and Gynaecol, University Hospital Carl Gustav Carus, Dresden, Germany,University Helsinki, Cent Hospital, Department Clin Genet, Helsinki, Finland
-
- Stoppa-Lyonnet, D. (author)
- University Paris 05, INSERM, U509, Serv Genet Oncol,Institute Curie, Paris, France
-
- De Pauw, A. (author)
- University Paris 05, INSERM, U509, Serv Genet Oncol,Institute Curie, Paris, France
-
- Mazoyer, S. (author)
- University Lyon 1, CNRS, Centre Leon Berard, Equipe Labellisee LIGUE 2008,UMR5201, F-69365 Lyon, France
-
- Bonadona, V. (author)
- University Lyon 1, CNRS, UMR5558, F-69365 Lyon, France
-
- Lasset, C. (author)
- University Lyon 1, CNRS, UMR5558, F-69365 Lyon, France
-
- Dreyfus, H. (author)
- CHU Grenoble, Department Genet, F-38043 Grenoble, France
-
- Leroux, D. (author)
- CHU Grenoble, Department Genet, F-38043 Grenoble, France
-
- Hardouin, A. (author)
- Centre Francois Baclesse, F-14021 Caen, France
-
- Berthet, P. (author)
- Centre Francois Baclesse, F-14021 Caen, France
-
- Faivre, L. (author)
- Centre Hospital University Dijon, Centre Genet, Dijon, France
-
- Loustalot, C. (author)
- Centre Lutte Canc Georges Francois Leclerc, Dijon, France
-
- Noguchi, T. (author)
- INSERM, Institute Paoli Calmettes, UMR599, Department Oncol Genet, F-13258 Marseille, France
-
- Sobol, H. (author)
- INSERM, Institute Paoli Calmettes, UMR599, Department Oncol Genet, F-13258 Marseille, France
-
- Rouleau, E. (author)
- Centre Rene Huguenin, INSERM, U735, St Cloud, France
-
Nogues, C. (author)
-
- Frénay, M. (author)
- Centre Antoine Lacassagne, F-06054 Nice, France
-
- Vénat-Bouvet, L. (author)
- Centre Hospital University Limoges, Department Oncol, Limoges, France
-
- Hopper, J. L. (author)
- University Copenhagen, Rigshosp, Department Clin Biochem, DK-2100 Copenhagen, Denmark
-
- Daly, M. B. (author)
- IEO, Div Canc Prevent and Genet, Milan, Italy,Fox Chase Canc Centre, Department Med Oncol, Womens Canc Program, Philadelphia, PA 19111 USA
-
- Terry, M. B. (author)
- Columbia University, New York, NY USA
-
John, E. M. (author)
-
- Buys, S. S. (author)
- University Utah, Hlth Science Centre, Huntsman Canc Institute, Salt Lake City, UT USA
-
- Yassin, Y. (author)
- Cedars Sinai Med Centre, Womens Canc Research Institute, Samuel Oschin Comprehens Canc Institute, Los Angeles, CA 90048 USA
-
Miron, A. (author)
-
Goldgar, D. (author)
-
- Singer, C. F. (author)
- Med University Vienna, Department Obstet and Gynecol, Vienna, Austria
-
- Dressler, A. C. (author)
- Med University Vienna, Department Obstet and Gynecol, Vienna, Austria
-
- Gschwantler-Kaulich, D. (author)
- Med University Vienna, Department Obstet and Gynecol, Vienna, Austria
-
- Pfeiler, G. (author)
- Med University Vienna, Department Obstet and Gynecol, Vienna, Austria
-
Hansen, T. V. O. (author)
-
Jnson, L. (author)
-
- Bergman, Annika (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics
-
- Kirchhoff, T. (author)
- Mem Sloan Kettering Canc Centre, Department Med, Clin Genet Serv, New York, NY 10021 USA
-
- Offit, K. (author)
- Mem Sloan Kettering Canc Centre, Department Med, Clin Genet Serv, New York, NY 10021 USA
-
- Devlin, V. (author)
- Mem Sloan Kettering Canc Centre, Department Med, Clin Genet Serv, New York, NY 10021 USA
-
- Dutra-Clarke, A. (author)
- Mem Sloan Kettering Canc Centre, Department Med, Clin Genet Serv, New York, NY 10021 USA
-
- Piedmonte, M. (author)
- Roswell Pk Canc Institute, GOG Stat and Data Centre, Buffalo, NY 14263 USA
-
- Rodriguez, G. C. (author)
- NorthShore University Hlth Syst, Evanston NW Healthcare, Evanston, IL USA
-
- Wakeley, K. (author)
- Tufts University, New England Med Centre, Boston, MA 02111 USA
-
- Boggess, J. F. (author)
- University N Carolina, Chapel Hill, NC USA
-
- Basil, J. (author)
- St Elizabeth Hospital, Edgewood, KY USA
-
- Schwartz, P. E. (author)
- Yale University, Sch Med, New Haven, CT USA
-
- Blank, S. V. (author)
- NYU, Sch Med, New York, NY USA
-
- Toland, A. E. (author)
- Ohio State University, Centre Comprehens Canc, Department Internal Med and Mol Virol, Div Human Canc Genet, Columbus, OH 43210 USA
-
Montagna, M. (author)
-
Casella, C. (author)
-
- Imyanitov, E. (author)
- NN Petrov Institute Oncol, St Petersburg, Russia
-
- Tihomirova, L. (author)
- Latvian Biomed Research and Study Centre, Riga, Latvia
-
- Blanco, I. (author)
- Catalan Institute Oncol IDIBELL, Hereditary Canc Program, Barcelona, Spain
-
- Lazaro, C. (author)
- Catalan Institute Oncol IDIBELL, Hereditary Canc Program, Barcelona, Spain
-
- Ramus, S. J. (author)
- University London Imperial Coll Science Technology and Med, Gynaecol Oncol Unit, UCL EGA Institute Womens Hlth, London, England,Centre Hospital University Quebec, Canada Research Chair Oncogenet, Canc Genom Lab, Quebec City, PQ, Canada
-
Sucheston, L. (author)
-
Karlan, B. Y. (author)
-
- Gross, J. (author)
- Cedars Sinai Med Centre, Womens Canc Research Institute, Samuel Oschin Comprehens Canc Institute, Los Angeles, CA 90048 USA
-
- Schmutzler, R. (author)
- University Cologne, Centre Familial Breast and Ovarian Canc, Department Obstet and Gynaecol, Cologne, Germany
-
- Wappenschmidt, B. (author)
- University Cologne, Centre Familial Breast and Ovarian Canc, Department Obstet and Gynaecol, Cologne, Germany
-
- Engel, C. (author)
- University Leipzig, Institute Med Informat Stat and Epidemiol, Leipzig, Germany
-
Meindl, A. (author)
-
- Lochmann, M. (author)
- Tech University Munich, Klinikum Rechts Isar, Department Obstet and Gynaecol, Div Tumor Genet, D-8000 Munich, Germany
-
- Arnold, N. (author)
- University Kiel, Department Obstet and Gynaecol, University Hospital Schleswig Holstein, Kiel, Germany
-
- Heidemann, S. (author)
- University Kiel, Institute Human Genet, University Hospital Schleswig Holstein, Kiel, Germany
-
- Varon-Mateeva, R. (author)
- Campus Virchow Klinikum, Charite Berlin, Institute Human Genet, Berlin, Germany
-
- Niederacher, D. (author)
- University Dusseldorf, Department Obstet and Gynaecol, Div Mol Genet, University Hospital Dusseldorf, Dusseldorf, Germany
-
- Sutter, C. (author)
- University Heidelberg, Institute Human Genet, Div Mol Diagnost, Heidelberg, Germany
-
- Deissler, H. (author)
- University Hospital Ulm, Department Obstet and Gynaecol, Ulm, Germany
-
Gadzicki, D. (author)
-
- Preisler-Adams, S. (author)
- University Hospital Muenster, Institute Human Genet, Munster, Germany
-
Kast, K. (author)
-
- Schönbuchner, I. (author)
- University Wurzburg, Institute Human Genet, Div Med Genet, Wurzburg, Germany
-
- Caldes, T. (author)
- Hospital Clin San Carlos, Mol Oncol Lab, Madrid, Spain
-
- De La Hoya, M. (author)
- Hospital Clin San Carlos, Mol Oncol Lab, Madrid, Spain
-
Aittomäki, K. (author)
-
- Nevanlinna, H. (author)
- University Helsinki, Cent Hospital, Department Obstet and Gynecol, FIN-00290 Helsinki, Finland
-
Simard, J. (author)
-
Spurdle, A. B. (author)
-
Holland, H. (author)
-
- Chen, X. (author)
- Queensland Institute Med Research, Brisbane, Qld, Australia
-
- Platte, R. (author)
- Center for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
-
- Chenevix-Trench, G. (author)
- Queensland Institute of Medical Research, Brisbane, Australia
-
Easton, D. F. (author)
-
- Bergman, Annika (contributor)
- Sahlgrenska University Hospital, Gothenburg, Sweden
-
- Einbeigi, Zakaria, 1962 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology
-
- Karlsson, Per, 1963 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology
-
- DallOlio, Valentina (author)
- Cogentech, Consortium Genom Technology, Milan, Italy
-
show less...
-
(creator_code:org_t)
-
- American Association for Cancer Research, 2010
- 2010
- English.
-
In: Cancer Research. - : American Association for Cancer Research. - 0008-5472 .- 1538-7445. ; 70:23, s. 9742-9754
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
https://urn.kb.se/re...
-
https://lup.lub.lu.s...
-
https://gup.ub.gu.se...
-
http://kipublication...
-
https://urn.kb.se/re...
-
show less...
Abstract
Subject headings
Close
- The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1, LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of 3 additional single nucleotide polymorphisms (SNPs), rs4973768 in SLC4A7/NEK10, rs6504950 in STXBP4/COX11, and rs10941679 at 5p12, and reanalyzed the previous associations using additional carriers in a sample of 12,525 BRCA1 and 7,409 BRCA2 carriers. Additionally, we investigated potential interactions between SNPs and assessed the implications for risk prediction. The minor alleles of rs4973768 and rs10941679 were associated with increased breast cancer risk for BRCA2 carriers (per-allele HR = 1.10, 95% CI: 1.03-1.18, P = 0.006 and HR = 1.09, 95% CI: 1.01-1.19, P = 0.03, respectively). Neither SNP was associated with breast cancer risk for BRCA1 carriers, and rs6504950 was not associated with breast cancer for either BRCA1 or BRCA2 carriers. Of the 9 polymorphisms investigated, 7 were associated with breast cancer for BRCA2 carriers (FGFR2, TOX3, MAP3K1, LSP1, 2q35, SLC4A7, 5p12, P = 7 × 10-11 - 0.03), but only TOX3 and 2q35 were associated with the risk for BRCA1 carriers (P = 0.0049, 0.03, respectively). All risk-associated polymorphisms appear to interact multiplicatively on breast cancer risk for mutation carriers. Based on the joint genotype distribution of the 7 risk-associated SNPs in BRCA2 mutation carriers, the 5% of BRCA2 carriers at highest risk (i.e., between 95th and 100th percentiles) were predicted to have a probability between 80% and 96% of developing breast cancer by age 80, compared with 42% to 50% for the 5% of carriers at lowest risk. Our findings indicated that these risk differences might be sufficient to influence the clinical management of mutation carriers.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- BRCA1 protein
- BRCA2 protein
- adult
- aged
- article
- attributable risk
- breast cancer
- cancer risk
- cancer susceptibility
- clinical evaluation
- controlled study
- female
- follow up
- gene frequency
- gene mutation
- genotype
- heterozygote
- human
- major clinical study
- priority journal
- probability
- risk assessment
- single nucleotide polymorphism
- tumor suppressor gene
- Aged
- 80 and over
- Alleles
- Breast Neoplasms
- Genetic Predisposition to Disease
- Humans
- Middle Aged
- Mutation
- Polymorphism
- Single Nucleotide
- Receptors
- Progesterone
- Risk Factors
- Sodium-Bicarbonate Symporters
- Survival Analysis
- Vesicular Transport Proteins
- MEDICINE
- Adult
- Aged
- Aged, 80 and over
- Alleles
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Female
- Genetic Predisposition to Disease
- Genotype
- Heterozygote
- Humans
- Middle Aged
- Mutation
- Polymorphism, Single Nucleotide
- Receptors, Progesterone
- Risk Assessment
- Risk Factors
- Sodium-Bicarbonate Symporters
- Survival Analysis
- Vesicular Transport Proteins
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Antoniou, A. C.
-
Beesley, J.
-
McGuffog, L.
-
Sinilnikova, O. ...
-
Healey, S.
-
Neuhausen, S. L.
-
show more...
-
Ding, Y. C.
-
Rebbeck, T. R.
-
Weitzel, J. N.
-
Lynch, H. T.
-
Isaacs, C.
-
Ganz, P. A.
-
Tomlinson, G.
-
Olopade, O. I.
-
Couch, F. J.
-
Wang, X.
-
Nordling, Margar ...
-
Pankratz, V. S.
-
Radice, P.
-
Manoukian, S.
-
Peissel, B.
-
Zaffaroni, D.
-
Stenmark-Askmalm ...
-
Viel, A.
-
Allavena, A.
-
Dall'Olio, V.
-
Peterlongo, P.
-
Szabo, C. I.
-
Zikan, M.
-
Claes, K.
-
Poppe, B.
-
Foretova, L.
-
Mai, P. L.
-
Greene, M. H.
-
Rennert, G.
-
Lejbkowicz, F.
-
Glendon, G.
-
Ozcelik, H.
-
Andrulis, I. L.
-
Thomassen, M.
-
Gerdes, A. -M
-
Sunde, L.
-
Cruger, D.
-
Jensen, U. B.
-
Caligo, M.
-
Friedman, E.
-
Kaufman, B.
-
Laitman, Y.
-
Milgrom, R.
-
Dubrovsky, M.
-
Cohen, S.
-
Borg, A.
-
Jernström, Helen ...
-
Lindblom, A.
-
Rantala, J.
-
Stenmark-Askmalm ...
-
Melin, Beatrice
-
Nathanson, K.
-
Domchek, S.
-
Jakubowska, A.
-
Lubinski, J.
-
Huzarski, T.
-
Osorio, A.
-
Lasa, A.
-
Durán, M.
-
Tejada, M. -I
-
Godino, J.
-
Benitez, J.
-
Hamann, U.
-
Kriege, M.
-
Hoogerbrugge, N.
-
Van Der Luijt, R ...
-
Van Asperen, C. ...
-
Devilee, P.
-
Meijers-Heijboer ...
-
Blok, M. J.
-
Aalfs, C. M.
-
Hogervorst, F.
-
Rookus, M.
-
Cook, M.
-
Oliver, C.
-
Frost, D.
-
Conroy, D.
-
Evans, D. G.
-
Lalloo, F.
-
Pichert, G.
-
Davidson, R.
-
Cole, T.
-
Cook, J.
-
Paterson, J.
-
Hodgson, S.
-
Morrison, P. J.
-
Porteous, M. E.
-
Walker, L.
-
Kennedy, M. J.
-
Dorkins, H.
-
Peock, S.
-
Godwin, A. K.
-
Stoppa-Lyonnet, ...
-
De Pauw, A.
-
Mazoyer, S.
-
Bonadona, V.
-
Lasset, C.
-
Dreyfus, H.
-
Leroux, D.
-
Hardouin, A.
-
Berthet, P.
-
Faivre, L.
-
Loustalot, C.
-
Noguchi, T.
-
Sobol, H.
-
Rouleau, E.
-
Nogues, C.
-
Frénay, M.
-
Vénat-Bouvet, L.
-
Hopper, J. L.
-
Daly, M. B.
-
Terry, M. B.
-
John, E. M.
-
Buys, S. S.
-
Yassin, Y.
-
Miron, A.
-
Goldgar, D.
-
Singer, C. F.
-
Dressler, A. C.
-
Gschwantler-Kaul ...
-
Pfeiler, G.
-
Hansen, T. V. O.
-
Jnson, L.
-
Bergman, Annika
-
Kirchhoff, T.
-
Offit, K.
-
Devlin, V.
-
Dutra-Clarke, A.
-
Piedmonte, M.
-
Rodriguez, G. C.
-
Wakeley, K.
-
Boggess, J. F.
-
Basil, J.
-
Schwartz, P. E.
-
Blank, S. V.
-
Toland, A. E.
-
Montagna, M.
-
Casella, C.
-
Imyanitov, E.
-
Tihomirova, L.
-
Blanco, I.
-
Lazaro, C.
-
Ramus, S. J.
-
Sucheston, L.
-
Karlan, B. Y.
-
Gross, J.
-
Schmutzler, R.
-
Wappenschmidt, B ...
-
Engel, C.
-
Meindl, A.
-
Lochmann, M.
-
Arnold, N.
-
Heidemann, S.
-
Varon-Mateeva, R ...
-
Niederacher, D.
-
Sutter, C.
-
Deissler, H.
-
Gadzicki, D.
-
Preisler-Adams, ...
-
Kast, K.
-
Schönbuchner, I.
-
Caldes, T.
-
De La Hoya, M.
-
Aittomäki, K.
-
Nevanlinna, H.
-
Simard, J.
-
Spurdle, A. B.
-
Holland, H.
-
Chen, X.
-
Platte, R.
-
Chenevix-Trench, ...
-
Easton, D. F.
-
Einbeigi, Zakari ...
-
Karlsson, Per, 1 ...
-
DallOlio, Valent ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
- Articles in the publication
-
Cancer Research
- By the university
-
Jönköping University
-
Umeå University
-
Uppsala University
-
Lund University
-
University of Gothenburg
-
Karolinska Institutet
-
show more...
-
Linköping University
-
show less...