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Physical exercise and internet-based cognitive-behavioural therapy in the treatment of depression : Randomised controlled trial

Hallgren, Mats (författare)
Karolinska Institutet,Department of Public Health Sciences, Section for Epidemiology and Public Health Intervention Research (EPHIR), Karolinska Institutet, Stockholm, Sweden
Kraepelien, Martin (författare)
Karolinska Institutet,Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Öjehagen, Agneta (författare)
Lund University,Lunds universitet,Psykiatri, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Psychiatry (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Clinical Science, Lund, Division of Psychiatry, Lund University, Lund, Sweden
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Lindefors, Nils (författare)
Karolinska Institutet,Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Zeebari, Zangin (författare)
Karolinska Institutet,Department of Public Health Sciences, Section for Epidemiology and Public Health Intervention Research (EPHIR), Karolinska Institutet, Stockholm, Sweden
Kaldo, Viktor (författare)
Karolinska Institutet,Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Forsell, Yvonne (författare)
Karolinska Institutet,Department of Public Health Sciences, Section for Epidemiology and Public Health Intervention Research (EPHIR), Karolinska Institutet, Stockholm, Sweden
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 (creator_code:org_t)
2018-01-02
2015
Engelska.
Ingår i: British Journal of Psychiatry. - : Cambridge University Press. - 0007-1250 .- 1472-1465. ; 207:3, s. 227-234
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background Depression is common and tends to be recurrent. Alternative treatments are needed that are non-stigmatising, accessible and can be prescribed by general medical practitioners.Aims To compare the effectiveness of three interventions for depression: physical exercise, internet-based cognitive-behavioural therapy (ICBT) and treatment as usual (TAU). A secondary aim was to assess changes in self-rated work capacity.Method A total of 946 patients diagnosed with mild to moderate depression were recruited through primary healthcare centres across Sweden and randomly assigned to one of three 12-week interventions (trail registry: KCTR study ID: KT20110063). Patients were reassessed at 3 months (response rate 78%).Results Patients in the exercise and ICBT groups reported larger improvements in depressive symptoms compared with TAU. Work capacity improved over time in all three groups (no significant differences).Conclusions Exercise and ICBT were more effective than TAU by a general medical practitioner, and both represent promising non-stigmatising treatment alternatives for patients with mild to moderate depression. 

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)
SAMHÄLLSVETENSKAP  -- Psykologi -- Tillämpad psykologi (hsv//swe)
SOCIAL SCIENCES  -- Psychology -- Applied Psychology (hsv//eng)

Nyckelord

adult
aged
alcohol consumption
anxiety disorder
Article
cognitive therapy
comparative effectiveness
controlled study
depression
disease severity
exercise
female
follow up
human
intermethod comparison
Internet
internet based cognitive behavioural therapy
job performance
major clinical study
male
Montgomery Asberg Depression Rating Scale
mood disorder
outcome assessment
primary health care
randomized controlled trial
sex difference
Sweden
treatment response
work capacity
adolescent
clinical trial
comparative study
Depressive Disorder
employment
kinesiotherapy
middle aged
multicenter study
multimodality cancer therapy
procedures
self concept
statistics and numerical data
treatment outcome
young adult
Combined Modality Therapy
Exercise Therapy
Humans
Self Efficacy
Work Capacity Evaluation
Psychology

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