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Combining populatio...
Combining population genomics and fitness QTLs to identify the genetics of local adaptation in Arabidopsis thaliana
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- Price, Nicholas (författare)
- Colorado State University, USA,Colorado State Univ, Dept Bioagr Sci & Pest Management, Ft Collins, CO 80523 USA
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- Moyers, Brook T. (författare)
- Colorado State University, USA,Colorado State Univ, Dept Bioagr Sci & Pest Management, Ft Collins, CO 80523 USA
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- Lopez, Lua (författare)
- Pennsylvania State University, USA,Penn State Univ, Dept Biol, University Pk, PA 16802 USA,Colorado State Univ, Dept Bioagr Sci & Pest Management, Ft Collins, CO 80523 USA
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- Lasky, Jesse R. (författare)
- Pennsylvania State University, USA,Penn State Univ, Dept Biol, University Pk, PA 16802 USA
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- Monroe, J. Grey (författare)
- Colorado State University, USA,Colorado State Univ, Dept Bioagr Sci & Pest Management, Ft Collins, CO 80523 USA
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- Mullen, Jack L. (författare)
- Colorado State University, USA
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- Oakley, Christopher G. (författare)
- urdue University, USA,Purdue Univ, Dept Bot & Plant Pathol, W Lafayette, IN 47907 USA;Purdue Univ, Ctr Plant Biol, W Lafayette, IN 47907 USA
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- Lin, Junjiang (författare)
- Colorado State University, USA,Colorado State Univ, Dept Bioagr Sci & Pest Management, Ft Collins, CO 80523 USA
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- Ågren, Jon (författare)
- Uppsala universitet,Växtekologi och evolution
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- Schrider, Daniel R. (författare)
- Rutgers State University, USA,Rutgers State Univ, Dept Genet, Piscataway, NJ 08854 USA
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- Kern, Andrew D. (författare)
- Rutgers State University, USA,Rutgers State Univ, Dept Genet, Piscataway, NJ 08854 USA
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- McKay, John K. (författare)
- Colorado State University, USA,Colorado State Univ, Dept Bioagr Sci & Pest Management, Ft Collins, CO 80523 USA
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(creator_code:org_t)
- 2018-04-23
- 2018
- Engelska.
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : NATL ACAD SCIENCES. - 0027-8424 .- 1091-6490. ; 115:19, s. 5028-5033
- Relaterad länk:
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https://doi.org/10.1...
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https://doi.org/10.1...
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https://www.pnas.org...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Evidence for adaptation to different climates in the model species Arabidopsis thaliana is seen in reciprocal transplant experiments, but the genetic basis of this adaptation remains poorly understood. Field-based quantitative trait locus (QTL) studies provide direct but low-resolution evidence for the genetic basis of local adaptation. Using high-resolution population genomic approaches, we examine local adaptation along previously identified genetic trade-off (GT) and conditionally neutral (CN) QTLs for fitness between locally adapted Italian and Swedish A. thaliana populations [angstrom gren J, et al. (2013) Proc Natl Acad Sci USA 110: 21077-21082]. We find that genomic regions enriched in high F-ST SNPs colocalize with GT QTL peaks. Many of these high F-ST regions also colocalize with regions enriched for SNPs significantly correlated to climate in Eurasia and evidence of recent selective sweeps in Sweden. Examining unfolded site frequency spectra across genes containing high F-ST SNPs suggests GTs may be due to more recent adaptation in Sweden than Italy. Finally, we collapse a list of thousands of genes spanning GT QTLs to 42 genes that likely underlie the observed GTs and explore potential biological processes driving these trade-offs, from protein phosphorylation, to seed dormancy and longevity. Our analyses link population genomic analyses and field-based QTL studies of local adaptation, and emphasize that GTs play an important role in the process of local adaptation.
Ämnesord
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
- NATURVETENSKAP -- Biologi -- Ekologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Ecology (hsv//eng)
Nyckelord
- divergent selection
- ecotype
- FST
- selective sweep
- tradeoff
- Biology
- Biologi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Price, Nicholas
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Moyers, Brook T.
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Lopez, Lua
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Lasky, Jesse R.
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Monroe, J. Grey
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Mullen, Jack L.
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visa fler...
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Oakley, Christop ...
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Lin, Junjiang
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Ågren, Jon
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Schrider, Daniel ...
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Kern, Andrew D.
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McKay, John K.
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- Om ämnet
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- NATURVETENSKAP
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NATURVETENSKAP
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och Biologi
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och Genetik
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- NATURVETENSKAP
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NATURVETENSKAP
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och Biologi
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och Ekologi
- Artiklar i publikationen
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Proceedings of t ...
- Av lärosätet
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Karlstads universitet
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Uppsala universitet