Smith Predictor Sliding Mode Closed-loop Glucose Controller in Type 1 Diabetes

• Type 1 diabetic patients depend on external insulin delivery to keep their blood glucose within near-normal ranges. In this work, two robust closed-loop controllers for blood glucose control are developed to prevent the life-threatening hypoglycemia, as well as to avoid extended hyperglycemia. The proposed controllers are designed by using the sliding mode control technique in a Smith predictor structure. To improve meal disturbance rejection, a simple feedforward controller is added to inject meal-time insulin bolus. Simulation studies were used to test the controllers, and shown the controllers ability to regulate the blood glucose within the safe limits in the presence of errors in measurements, modeling, and meal estimation.

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Elektroteknik och elektronik -- Reglerteknik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Electrical Engineering, Electronic Engineering, Information Engineering -- Control Engineering (hsv//eng)

Nyckelord

Type 1 diabetes Mellitus

glucose closed-loop control

Smith predictor

Publikations- och innehållstyp

ref (ämneskategori)

kon (ämneskategori)