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Contrast-enhanced s...
Contrast-enhanced spectral mammography with a photon-counting detector
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- Fredenberg, Erik, PhD, 1979- (författare)
- KTH,Medicinsk bildfysik,Medical Imaging
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Hemmendorff, Magnus (författare)
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- Cederström, Björn (författare)
- KTH,Medicinsk bildfysik,Medical Imaging
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Åslund, Magnus (författare)
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- Danielsson, Mats (författare)
- KTH,Medicinsk bildfysik,Medical Imaging
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(creator_code:org_t)
- 2010-04-12
- 2010
- Engelska.
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Ingår i: Medical physics (Lancaster). - : Wiley. - 0094-2405. ; 37:5, s. 2017-2029
- Relaterad länk:
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https://kth.diva-por... (primary) (Raw object)
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http://kth.diva-port...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Purpose: Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. In particular, the detectability of a contrast agent can be improved over a lumpy background. We have investigated a photon-counting spectral imaging system with two energy bins for contrast-enhanced mammography. System optimization and the potential benefit compared to conventional non-energy-resolved imaging was studied.Methods: A framework for system characterization was set up that included quantum and anatomical noise, and a theoretical model of the system was benchmarked to phantom measurements.Results: It was found that optimal combination of the energy-resolved images corresponded approximately to minimization of the anatomical noise, and an ideal-observer detectability index could be improved more than a factor of two compared to absorption imaging in the phantom study. In the clinical case, an improvement close to 80% was predicted for an average glandularity breast, and a factor of eight for dense breast tissue. Another 70% was found to be within reach for an optimized system.Conclusions: Contrast-enhanced spectral mammography is feasible and beneficial with the current system, and there is room for additional improvements.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Annan teknik -- Övrig annan teknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Other Engineering and Technologies -- Other Engineering and Technologies not elsewhere specified (hsv//eng)
- NATURVETENSKAP -- Data- och informationsvetenskap -- Datorseende och robotik (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Computer Vision and Robotics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
Nyckelord
- spectral imaging
- mammography
- contrast agent
- photon counting
- dual-energy subtraction
- energy weighting
- anatomical noise
- Other engineering physics
- Övrig teknisk fysik
- Image analysis
- Bildanalys
- Radiological research
- Radiologisk forskning
- Medical engineering
- Medicinsk teknik
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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