The Impact of Aortic Arch Geometry on Flow Characteristics

QC 20131206
Cardiovascular defects characterized by geometrical anomalies of the aorta and its eecton the blood ow is the focus of this study. Not only are the local ow characteristicsgeometry dependent, but they are also directly connected to the rheological properties ofblood. Flow characteristics such as wall shear stress are often postulated to play a centralrole in the development of vascular disease.In this study, blood is considered to be a non-Newtonian uid and modeled via theQuemada model, an empirical model that is valid for dierent red blood cell loading.Three patient-specic geometries of the aortic arch are investigated numerically. Thethree geometries investigated in this study all display malformations that are prevalent inpatients having the genetic disorder Turner syndrome. The results show a highly complexow with regions of secondary ow that are enhanced in two of the three aortas. Moreover,blood ow is clearly diverted due to the malformations, moving to a larger extent throughthe branches of the arch instead of through the descending aorta. The geometry havingan elongated transverse aorta is found to be subjected to larger areas of highly oscillatorylow wall shear stress.

TEKNIK OCH TEKNOLOGIER Maskinteknik Strömningsmekanik och akustik hsv//swe
ENGINEERING AND TECHNOLOGY Mechanical Engineering Fluid Mechanics and Acoustics hsv//eng
LES
aortic flow
healthy and disease
Flow characteristics
Genetic disorders
Non-Newtonian fluids
Patient specific
Rheological property
Turner syndrome
Vascular disease
Wall shear stress
Aerospace engineering
Arches
Blood
Geometry
Hemodynamics
Non Newtonian liquids
Rheology
Blood vessels

van Wyk, StevinKTH,Biomekanik,Linné Flow Center, FLOW(Swepub:kth)u1lhc7i5 (author)
Mihaescu, Mihai,1976-KTH,Mekanik,Linné Flow Center, FLOW(Swepub:kth)u1u92v2l (author)
Fuchs, LaszloKTH,Mekanik,Linné Flow Center, FLOW(Swepub:kth)u1820i1r (author)
Gutmark, EphraimAerospace Engineering, University of Cincinnati (author)
Backeljauw, PhilippeCincinnati Children's Hospital (author)
Gutmark-Little, IrisCincinnati Children's Hospital (author)
KTHBiomekanik (creator_code:org_t)

By the author/editor: Prahl-Wittberg, ...; van Wyk, Stevin; Mihaescu, Mihai, ...; Fuchs, Laszlo; Gutmark, Ephraim; Backeljauw, Phil ...; show more...; Gutmark-Little, ...; show less...

About the subject

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Mechanical Engin ...; and Fluid Mechanics ...

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