Search: id:"swepub:oai:DiVA.org:kth-124994" >
The genomics of sel...
The genomics of selection in dogs and the parallel evolution between dogs and humans
- Article/chapterEnglish2013
Publisher, publication year, extent ...
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2013-05-14
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Nature Publishing Group,2013
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:kth-124994
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https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-124994URI
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https://doi.org/10.1038/ncomms2814DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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QC 20130805
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The genetic bases of demographic changes and artificial selection underlying domestication are of great interest in evolutionary biology. Here we perform whole-genome sequencing of multiple grey wolves, Chinese indigenous dogs and dogs of diverse breeds. Demographic analysis show that the split between wolves and Chinese indigenous dogs occurred 32,000 years ago and that the subsequent bottlenecks were mild. Therefore, dogs may have been under human selection over a much longer time than previously concluded, based on molecular data, perhaps by initially scavenging with humans. Population genetic analysis identifies a list of genes under positive selection during domestication, which overlaps extensively with the corresponding list of positively selected genes in humans. Parallel evolution is most apparent in genes for digestion and metabolism, neurological process and cancer. Our study, for the first time, draws together humans and dogs in their recent genomic evolution.
Subject headings and genre
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NATURVETENSKAP Biologi hsv//swe
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NATURAL SCIENCES Biological Sciences hsv//eng
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animal experiment
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article
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biological phenomena and functions concerning the entire organism
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breed
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Chinese
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controlled study
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demography
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digestion
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dog
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domestication
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evolution
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gene sequence
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genetic selection
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genomics
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human
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human genome
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metabolism
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neoplasm
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neurology
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nonhuman
Added entries (persons, corporate bodies, meetings, titles ...)
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Zhai, Weiwei
(author)
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Yang, He-chuan
(author)
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Fan, Ruo-xi
(author)
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Cao, Xue
(author)
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Zhong, Li
(author)
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Wang, Lu
(author)
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Liu, Fei
(author)
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Wu, Hong
(author)
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Cheng, Lu-guang
(author)
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Poyarkov, Andrei D.
(author)
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Poyarkov, Nikolai A., Jr.
(author)
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Tang, Shu-sheng
(author)
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Zhao, Wen-ming
(author)
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Gao, Yun
(author)
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Lv, Xue-mei
(author)
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Irwin, David M.
(author)
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Savolainen, PeterKTH,Genteknologi,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1vb4l6u
(author)
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Wu, Chung-I
(author)
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Zhang, Ya-ping
(author)
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KTHGenteknologi
(creator_code:org_t)
Related titles
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In:Nature Communications: Nature Publishing Group4, s. 1860-2041-1723
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To the university's database
- By the author/editor
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Wang, Guo-dong
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Zhai, Weiwei
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Yang, He-chuan
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Fan, Ruo-xi
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Cao, Xue
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Zhong, Li
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show more...
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Wang, Lu
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Liu, Fei
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Wu, Hong
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Cheng, Lu-guang
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Poyarkov, Andrei ...
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Poyarkov, Nikola ...
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Tang, Shu-sheng
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Zhao, Wen-ming
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Gao, Yun
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Lv, Xue-mei
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Irwin, David M.
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Savolainen, Pete ...
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Wu, Chung-I
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Zhang, Ya-ping
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
- Articles in the publication
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Nature Communica ...
- By the university
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Royal Institute of Technology