Transaminations with isopropyl amine : equilibrium displacement with yeast alcohol dehydrogenase coupled to in situ cofactor regeneration

• Enantiopure chiral amines synthesis using omega-transaminases is hindered by an unfavourable equilibrium, but when using isopropylamine as the amine donor the equilibrium can be completely displaced by using a specific dehydrogenase in situ for removal of formed acetone.

Ämnesord

NATURVETENSKAP  -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)

NATURAL SCIENCES  -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)

Nyckelord

OPTICALLY-ACTIVE AMINES

ASYMMETRIC-SYNTHESIS

OMEGA-TRANSAMINASES

CHIRAL AMINES

Biochemistry

Biokemi

Publikations- och innehållstyp

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