Chitosan-N-poly(ethylene glycol) brush copolymers : Synthesis and adsorption on silica surface

• Chitosan-N-poly(ethylene glycol) brush copolymers with different degree of substitution (DS) were synthesized via reductive amination of chitosan by rnethoxy poly(ethylene glycol) (MPEG) aldehyde. Chitosan-N-MPEG copolymers were high-molecular-weight products with desirable DS; solubility and solution viscosity of those copolymers depended on the method of the synthesis of MPEG aldehyde and on DS. Synthesis of MPEG aldehyde by the use of TEMPO radical/BAIB was not suitable because of partial oxidation of methoxy groups of MPEG resulting in bifunctional PEG derivatives leading to cross-linking. Adsorption studies of chitosan-N-MPEG graft copolymers oil silica surface show that these polymers adsorb in highly hydrated layers.

Nyckelord

chitosan

poly(ethylene glycol)

water-soluble

graft copolymer

reductive amination

adsorption

QCM-D

reflectometry

peg-grafted chitosan

derivatives

oxidation

acetaldehyde

aldehydes

alcohols

acid

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