Unique pumping-out fracturing mechanism of a polymer-shelled contrast agent: An acoustic characterization and optical visualization

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: L773:0885 3010 OR L773:1525 8955 > Unique pumping-out ...

Details
MARC

Kothapalli, Veera Venkata Satya Naray,1985-KTH,Medicinsk bildteknik,Contrast Enhanced Medical Imaging (author)

Unique pumping-out fracturing mechanism of a polymer-shelled contrast agent : An acoustic characterization and optical visualization

Article/chapterEnglish2014

Publisher, publication year, extent ...

2014
printrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:kth-159768
https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-159768URI
https://doi.org/10.1109/TUFFC.2014.006732DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:130914379URI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

The study was financed by EU-grants (3MiCRON ) and strategic money from the Karolinska Institutet.QC 20150409
This work describes the fracturing mechanism of air-filled microbubbles (MBs) encapsulated by a cross-linked poly(vinyl alcohol) (PVA) shell. The radial oscillation and fracturing events following the ultrasound exposure were visualized with an ultrahigh-speed camera, and backscattered timedomain signals were acquired with the acoustic setup specific for harmonic detection. No evidence of gas emerging from defects in the shell with the arrival of the first insonation burst was found. In optical recordings, more than one shell defect was noted, and the gas core was drained without any sign of air extrusion when several consecutive bursts of 1 MPa amplitude were applied. In acoustic tests, the backscattered peak-to-peak voltage gradually reached its maximum and exponentially decreased when the PVA-based MB suspension was exposed to approximately 20 consecutive bursts arriving at pulse repetition frequencies of 100 and 500 Hz. Taking into account that the PVA shell is porous and possibly contains large air pockets between the cross-linked PVA chains, the aforementioned acoustic behavior might be attributed to pumping gas from these pockets in combination with gas release from the core through shell defects. We refer to this fracturing mechanism as pumping-out behavior, and this behavior could have potential use for the local delivery of therapeutic gases, such as nitric oxide.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

Daeichin, VeryaDepartment of Biomedical Engineering, Thoraxcenter, Erasmus MC, (author)
Mastik, FritsDepartment of Biomedical Engineering, Thoraxcenter, Erasmus MC (author)
Brodin, Lars-ÅkeKTH,Medicinsk bildteknik(Swepub:kth)u1jq9s27 (author)
Janerot Sjöberg, BirgittaKTH,Medicinsk teknik,Karolinska Institutet, Sweden; Karolinska University Hospital, Sweden(Swepub:kth)u1pw7lam (author)
Paradossi, GaioDiapartimento di Chimica, Università di Roma Tor Vergata (author)
de Jong, N.Department of Biomedical Engineering, Thoraxcenter, Erasmus MC (author)
Grishenkov, Dmitry,1983-KTH,Medicinsk bildteknik,Karolinska Institutet, Sweden; Karolinska University Hospital, Sweden,Contrast Enhanced Medical Imaging(Swepub:kth)u1b9avjc (author)
KTHMedicinsk bildteknik (creator_code:org_t)

Related titles

In:IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control62:3, s. 451-4620885-30101525-8955

Internet link

Find in a library

IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control (Search for host publication in LIBRIS)

To the university's database

Find more in SwePub

By the author/editor: Kothapalli, Veer ...; Daeichin, Verya; Mastik, Frits; Brodin, Lars-Åke; Janerot Sjöberg, ...; Paradossi, Gaio; show more...; de Jong, N.; Grishenkov, Dmit ...; show less...

About the subject

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Medical Equipmen ...

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Medical Image Pr ...

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Medical Material ...

Articles in the publication: IEEE Transaction ...

By the university: Royal Institute of Technology; Karolinska Institutet

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se