Testing and risk assessment of persistent and bioaccumulating chemical substances - Improvements within REACH?

• In the proposed new European chemicals regulations - the REACH system - the improved control of persistent and bioaccumulating substances is stated as one of the tasks being of particular importance. In this article, the reliability and validity of the scientific basis for identification of persistent ( P), bioaccumulating ( B), and toxic ( T) substances, and for assessing the risks that these substances may pose, are discussed. We have used the European Union risk assessment of pentabromodiphenyl ether, PentaBDE ( CAS 32534-81-9) as a study case in the analysis. It is concluded that for PBT substances there is room for development both with regard to test methodology and with regard to risk assessment procedures.

Nyckelord

REACH

risk assessment

PBT

vPvB

PentaBDE

CAS 32534-81-9

cytochrome-p450 activity

harpacticoid copepod

liver morphology

reproduction

constants

sediment

exposure

pbdes

water

fish

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)