Carbohydrate conjugation through microwave-assisted functionalization of single-walled carbon nanotubes using perfluorophenyl azides

Kong, NaKTH,Organisk kemi,Royal Institute of Technology, Department of Chemistry (författare)

QC 20150505.Correction in: Carbohydrate Research, Vol. 412, article number 6968, DOI: 10.1016/j.carres.2015.03.013, WOS: 000357542000012, Scopus: 2-s2.0-84934753187
Upprättat; 2016; 20160413 (inah)
Carbohydrate-functionalized single-walled carbon nanotubes (SWNTs) were synthesized using microwave-assisted reaction of perfluorophenyl azide with the nanotubes. The results showed that microwave radiation provides a rapid and effective means to covalently attach carbohydrates to SWNTs, producing carbohydrate-SWNT conjugates for biorecognition. The carbohydrate-functionalized SWNTs were furthermore shown to interact specifically with cognate carbohydrate-specific proteins (lectins), resulting in predicted recognition patterns. The carbohydrate-presenting SWNTs constitute a new platform for sensitive protein-or cell recognition, which pave the way for glycoconjugated carbon nanomaterials in biorecognition applications.

Shimpi, Manishkumar R.KTH,Organisk kemi,Royal Institute of Technology, Department of Chemistry(Swepub:ltu)manshi (författare)
Park, Jae HyeungDepartment of Chemistry, University of Massachusetts, Lowell (författare)
Ramström, OlofKTH,Organisk kemi,Organic Chemistry, School of Chemical Science and Engineering, KTH – Royal Institute of Technology, Stockholm, Royal Institute of Technology, Department of Chemistry(Swepub:kth)u1aj7snf (författare)
Yan, MingdiKTH,Organisk kemi,Royal Institute of Technology, Department of Chemistry(Swepub:kth)u11pqx4f (författare)
KTHOrganisk kemi (creator_code:org_t)

Av författaren/redakt...: Kong, Na; Shimpi, Manishku ...; Park, Jae Hyeung; Ramström, Olof; Yan, Mingdi

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