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Na+, K+-ATPase, a n...
Na+, K+-ATPase, a new class of plasma membrane receptors
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- Aperia, Anita Chatarina (författare)
- Karolinska Institutet
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Akkuratov, Evgeny E (författare)
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- Fontana, Jacopo Maria (författare)
- KTH,Cellens fysik
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- Brismar, Hjalmar (författare)
- Karolinska Institutet,KTH,Cellens fysik
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(creator_code:org_t)
- American Physiological Society, 2016
- 2016
- Engelska.
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Ingår i: American Journal of Physiology - Cell Physiology. - : American Physiological Society. - 0363-6143 .- 1522-1563. ; 310:7, s. C491-C495
- Relaterad länk:
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https://www.physiolo...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- The Na(+), K(+)-ATPase (NKA) differs from most other ion transporters not only in its capacity to maintain a steep electrochemical gradient across the plasma membrane but also as a receptor for a family of cardiotonic steroids, to which ouabain belongs. Studies from many groups, performed during the last fifteen years, have demonstrated that ouabain, a member of the cardiotonic steroid family, can activate a network of signaling molecules and that NKA will also serve as a signal transducer that can provide a feed back loop between NKA and the mitochondria. This brief review summarizes the current knowledge and controversies with regard to the understanding of NKA signaling.
Ämnesord
- NATURVETENSKAP -- Fysik -- Annan fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Other Physics Topics (hsv//eng)
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
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- art (ämneskategori)
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