Sökning: WFRF:(Hallström Björn M)
> (2016) >
Transcriptomics res...
Transcriptomics resources of human tissues and organs
-
- Uhlén, Mathias (författare)
- KTH,Proteomik och nanobioteknologi,Science for Life Laboratory, SciLifeLab,Technical University of Denmark, Denmark,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden.;KTH Royal Inst Technol, Dept Prote, Stockholm, Sweden.;Tech Univ Denmark, Novo Nordisk Fdn, Ctr Biosustainabil, Horsholm, Denmark.,Kungliga Tekniska Högskolan (KTH),Royal Institute of Technology (KTH),Danmarks Tekniske Universitet
-
- Hallström, Björn M. (författare)
- KTH,Proteomik och nanobioteknologi,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden.;KTH Royal Inst Technol, Dept Prote, Stockholm, Sweden.,Kungliga Tekniska Högskolan (KTH),Royal Institute of Technology (KTH)
-
- Lindskog Bergström, Cecilia (författare)
- Uppsala universitet,Institutionen för immunologi, genetik och patologi,Uppsala University
-
visa fler...
-
- Mardinoglu, Adil (författare)
- KTH,Proteomik och nanobioteknologi,Science for Life Laboratory, SciLifeLab,Chalmers University of Technology, Sweden,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden.;Chalmers, Dept Biol & Biol Engn, S-41296 Gothenburg, Sweden.,Chalmers tekniska högskola
-
- Pontén, Fredrik (författare)
- Uppsala universitet,Institutionen för immunologi, genetik och patologi,Uppsala University
-
- Nielsen, Jens (författare)
- KTH,Genteknologi,Science for Life Laboratory, SciLifeLab,Technical University of Denmark, Denmark; Chalmers University of Technology, Sweden,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden.;Tech Univ Denmark, Novo Nordisk Fdn, Ctr Biosustainabil, Horsholm, Denmark.;Chalmers, Dept Biol & Biol Engn, S-41296 Gothenburg, Sweden.,Chalmers tekniska högskola,Chalmers University of Technology
-
visa färre...
-
(creator_code:org_t)
- 2016-04-04
- 2016
- Engelska.
-
Ingår i: Molecular Systems Biology. - : Blackwell Publishing. - 1744-4292 .- 1744-4292. ; 12:4
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://doi.org/10.1...
-
https://uu.diva-port... (primary) (Raw object)
-
http://publications.... (primary) (free)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
https://research.cha...
-
visa färre...
Abstract
Ämnesord
Stäng
- Quantifying the differential expression of genes in various human organs, tissues, and cell types is vital to understand human physiology and disease. Recently, several large-scale transcriptomics studies have analyzed the expression of protein-coding genes across tissues. These datasets provide a framework for defining the molecular constituents of the human body as well as for generating comprehensive lists of proteins expressed across tissues or in a tissue-restricted manner. Here, we review publicly available human transcriptome resources and discuss body-wide data from independent genome-wide transcriptome analyses of different tissues. Gene expression measurements from these independent datasets, generated using samples from fresh frozen surgical specimens and postmortem tissues, are consistent. Overall, the different genome-wide analyses support a distribution in which many proteins are found in all tissues and relatively few in a tissue-restricted manner. Moreover, we discuss the applications of publicly available omics data for building genome-scale metabolic models, used for analyzing cell and tissue functions both in physiological and in disease contexts.
Ämnesord
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)
Nyckelord
- genome-scale metabolic models
- proteomics
- transcriptomics
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
Hitta via bibliotek
Till lärosätets databas