Interactive crystallomic

• Biologically important molecules have to be crystallized from solution before their atomic structures can be determined. Once their structures have been determined, reliable and fine structural details, which are crucial for structure-based drug design, can be obtained. Crystallization is an important but very poorly understood process. Our inability to produce good quality crystals is a severe limitation of protein crystallography. In this chapter we present rational guidelines which aim to alter our know-how on crystallization from “black magic” into quantitative and affordable science. We have coined a new word, crystallomic, which can be applied to a diverse range of molecules and may intensify research related to crystallogenesis.

Subject headings

NATURVETENSKAP  -- Kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences (hsv//eng)

Keyword

Crystallization

Crystallization screens

Crystallomic

Crystals

Factorial design

Proteins

Virus

Publication and Content Type

vet (subject category)

kap (subject category)