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Sökning: L773:0925 4439 > (2000-2004) > Low-frequency low-f...

  • Allen, P. D. (författare)

Low-frequency low-field magnetic susceptibility of ferritin and hemosiderin

  • Artikel/kapitelEngelska2000

Förlag, utgivningsår, omfång ...

  • 2000
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:kth-19569
  • https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-19569URI
  • https://doi.org/10.1016/S0925-4439(99)00104-0DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • QC 20100525
  • Low-frequency low-field magnetic susceptibility measurements were made on four samples of mammalian tissue iron oxide deposits. The samples comprised: (1) horse spleen ferritin; (') dugong liver hemosiderin; (3) thalassemic human spleen ferritin; and (4) crude thalassemic human spleen hemosiderin. These samples were chosen because Mossbauer spectroscopic measurements on the samples indicated that they exemplified the variation in magnetic and mineral structure found in mammalian tissue iron oxide deposits. The AC-magnetic susceptometry yielded information on the magnetization kinetics of the four samples indicating samples 1, 2, and 3 to be superparamagnetic with values of around 10(11) s(-1) for the preexponential frequency factor in the Neel-Arrhenius equation and values for characteristic magnetic anisotropy energy barriers in the range 250-400 K. Sample 4 was indicated to he paramagnetic at all temperatures above 1.3 K. The AC-magnetic susceptometry data also indicated a larger magnetic anisotropy energy distribution in the dugong liver sample compared with samples 1 and 3 in agreement with previous Mossbauer spectroscopic data on these samples. At temperatures below 200 K, samples 1-3 exhibited Curie-Weiss law behavior, indicating weak particle-particle interactions tending to favor antiparallel alignment of the particle magnetic moments. These interactions were strongest for the dugong liver hemosiderin. possibly reflecting the smaller separation between mineral particles in this sample. This is the first magnetic susceptometry study of hemosiderin iron deposits and demonstrates that the AC-magnetic susceptometry technique is a fast and informative method of studying such tissue iron oxide deposits.

Ämnesord och genrebeteckningar

  • AC-magnetic susceptibility
  • ferritin
  • hemosiderin
  • superparamagnetism
  • iron oxide
  • Mossbauer spectroscopy
  • iron-oxide deposits
  • thalassemia hemoglobin-e
  • mossbauer-spectroscopy
  • overload diseases
  • cores
  • tissues
  • spleen
  • limpet

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • St Pierre, T. G. (författare)
  • Chua-anusorn, W. (författare)
  • Ström, ValterKTH,Materialvetenskap(Swepub:kth)u1u6wc2n (författare)
  • Rao, K. V. (författare)
  • KTHMaterialvetenskap (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Biochimica et Biophysica Acta - Molecular Basis of Disease1500:2, s. 186-1960925-44391879-260X

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