Characterization and MRI study of surfactant-coated superparamagnetic nanoparticles administered into the rat brain

• A pre-clinical study has been carried out for the utilization of magnetite (Fe-3 O-4) nanoparticles as a diagnostic tracer for MRI. Surfactant-coated Fe3O4 nanoparticles have been synthesized by a chemical coprecipitation method with a narrow particle size of around 6 nm. Preliminary experiments demonstrated the feasibility of using superparamagnetic Fe-3 O-4 nanoparticles as contrast agents in MR imaging.

Nyckelord

nanoparticles

superparamagnetism

MRI

iron oxide

brain

rat

contrast agent

gene-expression

kinetics

galanin

Publikations- och innehållstyp

ref (ämneskategori)

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