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  • Brasko, Csilla (author)

Intelligent image-based in situ single-cell isolation

  • Article/chapterEnglish2018

Publisher, publication year, extent ...

  • 2018-01-15
  • NATURE PUBLISHING GROUP,2018
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:kth-221926
  • https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-221926URI
  • https://doi.org/10.1038/s41467-017-02628-4DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • QC 20180131
  • Quantifying heterogeneities within cell populations is important for many fields including cancer research and neurobiology; however, techniques to isolate individual cells are limited. Here, we describe a high-throughput, non-disruptive, and cost-effective isolation method that is capable of capturing individually targeted cells using widely available techniques. Using high-resolution microscopy, laser microcapture microscopy, image analysis, and machine learning, our technology enables scalable molecular genetic analysis of single cells, targetable by morphology or location within the sample.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Smith, Kevin,1975-KTH,Beräkningsvetenskap och beräkningsteknik (CST),Science for Life Laboratory, SciLifeLab(Swepub:kth)u1l33jpf (author)
  • Molnar, Csaba (author)
  • Farago, Nora (author)
  • Hegedus, Lili (author)
  • Balind, Arpad (author)
  • Balassa, Tamas (author)
  • Szkalisity, Abel (author)
  • Sukosd, Farkas (author)
  • Kocsis, Katalin (author)
  • Balint, Balazs (author)
  • Paavolainen, Lassi (author)
  • Enyedi, Marton Z. (author)
  • Nagy, Istvan (author)
  • Puskas, Laszlo G. (author)
  • Haracska, Lajos (author)
  • Tamas, Gabor (author)
  • Horvath, Peter (author)
  • KTHBeräkningsvetenskap och beräkningsteknik (CST) (creator_code:org_t)

Related titles

  • In:Nature Communications: NATURE PUBLISHING GROUP92041-1723

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