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Role of A-current i...
Role of A-current in lamprey locomotor network neurons
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- Huss, Mikael (author)
- KTH,Numerisk analys och datalogi, NADA
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Hess, Dietmar (author)
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d'Incamps, Boris Lamotte (author)
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El Manira, Abdeljabbar (author)
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- Lansner, Anders (author)
- KTH,Numerisk analys och datalogi, NADA
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- Hellgren Kotaleski, Jeanette (author)
- KTH,Numerisk analys och datalogi, NADA
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(creator_code:org_t)
- Elsevier BV, 2003
- 2003
- English.
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In: Neurocomputing. - : Elsevier BV. - 0925-2312 .- 1872-8286. ; 52-54, s. 295-300
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- A compartmental model of lamprey central pattern generator neurons was built in order to examine the effects of a fast, transient, high-voltage-activated potassium current (A-current) found experimentally. The model consisted of a soma, a compartment corresponding to the axon initial segment, and a dendritic tree. The simulation showed that the A-current was necessary for repetitive spiking in the single neuron following current injection. The functional role of adding an A-current was also examined in a network model. In this model, the A-current stabilizes the swimming rhythm by making the burst cycle duration and the number of spikes per burst less variable. All these effects are also seen experimentally.
Subject headings
- NATURVETENSKAP -- Data- och informationsvetenskap -- Datorteknik (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Computer Engineering (hsv//eng)
Keyword
- A-current
- lamprey
- potassium
- CPG
- Hodgkin-Huxley
- Computer engineering
- Datorteknik
Publication and Content Type
- ref (subject category)
- art (subject category)
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