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Automatic rat brain...
Automatic rat brain segmentation from MRI using statistical shape models and random forest
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- Bendazzoli, Simone (författare)
- KTH,Medicinteknik och hälsosystem,KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Halsovagen 11, S-14157 Huddinge, Sweden
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- Brusini, Irene (författare)
- KTH,Medicinsk avbildning,KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Halsovagen 11, S-14157 Huddinge, Sweden;Karolinska Inst, Dept Neurobiol Care Sci & Soc, Alfred Nobels Alle 23,D3, S-14152 Huddinge, Sweden
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- Damberg, Peter (författare)
- Karolinska Inst, Dept Clin Neurosci, Tomtebodavagen 18A P1 5, S-17177 Stockholm, Sweden.
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- Smedby, Örjan, Professor, 1956- (författare)
- KTH,Medicinsk avbildning,KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Halsovagen 11, S-14157 Huddinge, Sweden
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- Andersson, Leif (författare)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab
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- Wang, Chunliang, 1980- (författare)
- KTH,Medicinsk avbildning,KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Halsovagen 11, S-14157 Huddinge, Sweden
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(creator_code:org_t)
- SPIE-INT SOC OPTICAL ENGINEERING, 2019
- 2019
- Engelska.
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Ingår i: MEDICAL IMAGING 2019. - : SPIE-INT SOC OPTICAL ENGINEERING. - 9781510625464 - 9781510625457
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- In MRI neuroimaging, the shimming procedure is used before image acquisition to correct for inhomogeneity of the static magnetic field within the brain. To correctly adjust the field, the brain's location and edges must first be identified from quickly-acquired low resolution data. This process is currently carried out manually by an operator, which can be time-consuming and not always accurate. In this work, we implement a quick and automatic technique for brain segmentation to be potentially used during the shimming. Our method is based on two main steps. First, a random forest classifier is used to get a preliminary segmentation from an input MRI image. Subsequently, a statistical shape model of the brain, which was previously generated from ground-truth segmentations, is fitted to the output of the classifier to obtain a model-based segmentation mask. In this way, a-priori knowledge on the brain's shape is included in the segmentation pipeline. The proposed methodology was tested on low resolution images of rat brains and further validated on rabbit brain images of higher resolution. Our results suggest that the present method is promising for the desired purpose in terms of time efficiency, segmentation accuracy and repeatability. Moreover, the use of shape modeling was shown to be particularly useful when handling low-resolution data, which could lead to erroneous classifications when using only machine learning-based methods.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Image Processing (hsv//eng)
Nyckelord
- brain MRI
- image segmentation
- shimming
- random forest
- statistical shape model
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)
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