WFRF:(Wester Per 1959 )
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- Isaksson, EvaKarolinska Institutet,Karolinska Inst, Dept Clin Neurosci, Neurol, Nobels Vag 6, SE-17176 Stockholm, Sweden (author)
Identifying important barriers to recruitment of patients in randomised clinical studies using a questionnaire for study personnel
- Article/chapterEnglish2019
Publisher, publication year, extent ...
- 2019-10-30
- BMC,2019
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:kth-266224
- https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-266224URI
- https://doi.org/10.1186/s13063-019-3737-1DOI
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167043URI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:142479719URI
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-400767URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- QC 20200109
- Background: Many randomised controlled trials (RCT) fail to meet their recruitment goals. Study personnel play a key role in recruitment. The aim of this study was to identify successful strategies that study personnel consider to be important in patient recruitment to RCT. Methods: We constructed a questionnaire based on the literature, discussions with colleagues and our own experience as trialists. The survey was named "What is Important for Making a Study Successful questionnaire" (WIMSS-q). Our target group was the study personnel in the ongoing EFFECTS study. The questionnaire was sent out electronically to all physicians and nurses (n = 148). Success factors and barriers were divided according to patient, centre and study level, respectively. Results: Responses were received from 94% of the study personnel (139/148). The five most important factors at centre level for enhancing recruitment were that the research question was important (97%), a simple procedure for providing information and gaining consent (92%), a highly engaged local principal investigator and research nurse (both 87%), and that study-related follow-ups are practically feasible and possible to coordinate with the clinical follow-up (87%). The most significant barrier at the local centre was lack of time and resources devoted to research (72%). Important patient-related barriers were fear of side effects (35%) and language problems (30%). Conclusions: For recruitment in an RCT to be successful, the research question must be relevant, and the protocol must be simple and easy to implement in the daily routine.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap hsv//swe
- MEDICAL AND HEALTH SCIENCES Health Sciences hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
- Recruitment
- Survey
- Questionnaire
- Randomised controlled trials
- RCT
Added entries (persons, corporate bodies, meetings, titles ...)
- Wester, Per,1959-Karolinska Institutet,Umeå universitet,Avdelningen för medicin,Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, SE-18288 Stockholm, Sweden,Danderyd Hosp, Karolinska Inst, Dept Clin Sci, SE-18288 Stockholm, Sweden.;Umeå Univ, Dept Publ Hlth & Clin Med, S-90187 Umeå, Sweden.(Swepub:umu)pewe0002 (author)
- Laska, Ann CharlotteKarolinska Institutet,Danderyd Hosp, Karolinska Inst, Dept Clin Sci, SE-18288 Stockholm, Sweden (author)
- Näsman, Per,1954-KTH,Bygg- och fastighetsekonomi,Fastighetsekonomi och finans,KTH Royal Inst Technol, Ctr Safety Res, SE-10044 Stockholm, Sweden(Swepub:kth)u1ghoqwp (author)
- Lundström, Erik,Docent,1964-Uppsala universitet,Karolinska Institutet,Landtblom: Neurovetenskap(Swepub:uu)erlun676 (author)
- Karolinska InstitutetKarolinska Inst, Dept Clin Neurosci, Neurol, Nobels Vag 6, SE-17176 Stockholm, Sweden (creator_code:org_t)
Related titles
- In:Trials: BMC20:11745-6215
Internet link
- https://doi.org/10.1186/s13063-019-3737-1Fulltext
- https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-019-3737-1
- https://umu.diva-portal.org/smash/get/diva2:1383807/FULLTEXT01.pdffulltext:print
- https://uu.diva-portal.org/smash/get/diva2:1382470/FULLTEXT01.pdffulltext:print
- https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-266224
- https://doi.org/10.1186/s13063-019-3737-1
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167043
- http://kipublications.ki.se/Default.aspx?queryparsed=id:142479719
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-400767
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