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Minimise thermo-mec...
Minimise thermo-mechanical batch variations when processing medical grade lactide based copolymers in additive manufacturing
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- Ahlinder, Astrid (författare)
- KTH,Polymerteknologi
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- Charlon, Sebastien (författare)
- IMT Lille Douai, Ecole nationale supérieure Mines-Télécom Lille Douai, Materials & Processes Center, Cité scientifique, Villeneuve d'Ascq Cedex, France
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- Fuoco, Tiziana, PhD, 1986- (författare)
- KTH,Polymerteknologi
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- Soulestin, Jeremie (författare)
- IMT Lille Douai, Ecole nationale supérieure Mines-Télécom Lille Douai, Materials & Processes Center, Cité scientifique, Villeneuve d'Ascq Cedex, France
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- Finne Wistrand, Anna, 1976- (författare)
- KTH,Polymerteknologi
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(creator_code:org_t)
- Elsevier BV, 2020
- 2020
- Engelska.
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Ingår i: Polymer degradation and stability. - : Elsevier BV. - 0141-3910 .- 1873-2321. ; 181
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Additive manufacturing is suitable for producing complex geometries; however, variation in thermo-mechanical properties are observed during one batch cycle when degradable aliphatic polyesters of medical grade are used in melt extrusion-based methods. This is one important reason for why additive manufacturing has not yet been fully utilised to produce degradable medical implants. Herein, the internal variation has been minimised during one batch cycle by assessing the effect of different processing parameters when using commercially available medical grade copolymers. To minimise the molar mass, thermal and mechanical variation within one batch cycle, the rheological fingerprint of the commercially available medical grade poly(L-lactide-co-ε-caprolactone) and poly(L-lactide-co-trimethylene carbonate) has been correlated to the process parameters of the ARBURG Plastic Freeforming. An increase in the temperature up to 220°C and the associated increase in pressure are beneficial for the viscoelastic and thermally stable poly(L-lactide-co-ε-caprolactone). In contrast, a temperature below 220°C should be used for the poly(L-lactide-co-trimethylene carbonate) to reduce the variation in strain at break during one batch cycle. The residence time is decreased through the increase of the discharge parameter. An increase in temperature is however required to reduce the viscosity of the polymer and allow the pressure to stay within the machine limitations at higher discharge parameters. The results are highly relevant to the development of additive manufacturing for the production of degradable medical devices with identical properties. In fact, Food and Drug Administration guidelines for additive manufacturing of medical implants specify the need to control changes in material properties during the process.
Ämnesord
- NATURVETENSKAP -- Kemi -- Polymerkemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Polymer Chemistry (hsv//eng)
Nyckelord
- Additive manufacturing
- e-caprolactone
- Freeforming
- L-lactide
- medical device
- polyester
- polymer degradation
- trimethylene carbonate
- Aliphatic compounds
- Food additives
- Functional polymers
- Melt spinning
- Aliphatic polyester
- Discharge parameters
- Food and Drug Administration
- Increase in pressure
- Mechanical variations
- Processing parameters
- Thermomechanical properties
- 3D printers
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- art (ämneskategori)
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