L773:0021 8502
Search: L773:0021 8502 > Regional deposition...
- 49 of 95
- Previous record
- Next record
- To hitlist
- Hazeri, Mohammad (author)
Regional deposition of the allergens and micro-aerosols in the healthy human nasal airways
- Article/chapterEnglish2021
Publisher, publication year, extent ...
- Elsevier BV,2021
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:kth-289520
- https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-289520URI
- https://doi.org/10.1016/j.jaerosci.2020.105700DOI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- QC 20210202
- The nasal cavity is the inlet to the human respiratory system and is responsible for the olfactory sensation, filtering pollutant particulate matter, and humidifying the air. Many research studies have been performed to numerically predict allergens, contaminants, and/or drug particle deposition in the human nasal cavity; however, the majority of these investigations studied only one or a small number of nasal passages. In the present study, a series of Computed Tomography (CT) scan images of the nasal cavities from ten healthy subjects were collected and used to reconstruct accurate 3D models. All models were divided into twelve anatomical regions in order to study the transport and deposition features of different regions of the nasal cavity with specific functions. The flow field and micro-particle transport equations were solved, and the total and regional particle deposition fractions were evaluated for the rest and low activity breathing conditions. The results show that there are large variations among different subjects. The standard deviation of the total deposition fraction in the nasal cavities was the highest for 5 x 10(4) impaction parameter (IP)<1.125 x 10(5) with a maximum of 20%. The achieved results highlighted the nasal cavity sections that are more involved in the particle deposition. Particles with IP = 30,000 deposit more in the middle turbinate and nasopharynx areas, while for particles with IP = 300,000, deposition is mainly in the anterior parts (kiesselbach and vestibule regions). For small IP values, the amounts of deposition fractions in different regions of the nasal cavity are more uniform.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng
- CFD
- Nasal cavity
- Particle deposition
- Regional deposition
- Allergen
- Nose-to-brain drug delivery
Added entries (persons, corporate bodies, meetings, titles ...)
- Faramarzi, Mohammad (author)
- Sadrizadeh, SasanKTH,Hållbara byggnader(Swepub:kth)u1my1c70 (author)
- Ahmadi, Goodarz (author)
- Abouali, Omid (author)
- KTHHållbara byggnader (creator_code:org_t)
Related titles
- In:Journal of Aerosol Science: Elsevier BV1520021-85021879-1964
Internet link
Find in a library
- Journal of Aerosol Science (Search for host publication in LIBRIS)
To the university's database
- 49 of 95
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Hazeri, Mohammad
- Faramarzi, Moham ...
- Sadrizadeh, Sasa ...
- Ahmadi, Goodarz
- Abouali, Omid
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- Articles in the publication
- Journal of Aeros ...
- By the university
- Royal Institute of Technology
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
