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Optimized electrochemical breakdown etching using temporal voltage variation for formation of nanopores in a silicon membrane

Chung, Nguyen Xuan (författare)
KTH,Fotonik,Hanoi Univ Min & Geol, Dept Phys, 18 Pho Vien, Hanoi, Vietnam.,Nanosilicon Group
Gatty, Hithesh Kumar (författare)
KTH,Fotonik,Nanosilicon Group
Lu, Xi (författare)
KTH,Fotonik,Nanosilicon Group
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Zhang, Miao, 1985- (författare)
KTH,Fotonik,Ecole Polytech Fed Lausanne EPFL, Inst Bioengn, Sch Engn, CH-1015 Lausanne, Switzerland.
Linnros, Jan, 1953- (författare)
KTH,Fotonik
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 (creator_code:org_t)
Elsevier BV, 2021
2021
Engelska.
Ingår i: Sensors and actuators. B, Chemical. - : Elsevier BV. - 0925-4005 .- 1873-3077. ; 331
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Dielectric breakdown etching is a well-known method of making nanopores on thin (similar to 50 nm) dielectric membranes. However, voltage driven translocation of biomolecules through such nanopores becomes extremely fast. For improved detection, for instance by the current blockage, a high-aspect-ratio nanopore could be beneficial for slowing down the translocation. High-aspect-ratio nanopore on silicon fabrication requires a well-controlled process and is dependent on specific crystal orientation, dopant type and resistivity of substrate. Therefore, an optimized method of processing high-aspect-ratio nanopores is necessary considering the advantage of a silicon membrane being able to be integrated with standard CMOS processing. Here, we present an optimized fabrication method for mass-producing a single and an array of nanopores on a thick (2 mu m) silicon device layer based on a silicon-on-insulator (SOI) wafer. A method of temporal voltage variation is exploited to optimize the etching parameters for the nanopore formation during electrochemical breakdown etching, diameters of nanopores around 12 nm have been achieved. Besides, the correlation between the parameters of etching and nanopore diameter is deduced. The processed high-aspect-ratio nanopore enables applications in single-molecule sensing such as DNA, exosomes, viruses, and protein markers. The developed process is inexpensive, fast and can be batch fabricated.

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Elektroteknik och elektronik -- Annan elektroteknik och elektronik (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Electrical Engineering, Electronic Engineering, Information Engineering -- Other Electrical Engineering, Electronic Engineering, Information Engineering (hsv//eng)

Nyckelord

Nanopore
Electrochemical breakdown etching
High-aspect-ratio
Silicon membranes

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