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Long-term prognosis...
Long-term prognosis after a first myocardial infarction : eight years follow up of the case-control study PAROKRANK
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- Ferrannini, Giulia (författare)
- Karolinska Institutet,Karolinska Institute
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- Almosawi, Mariam (författare)
- Karolinska Institute
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- Buhlin, Kare (författare)
- Karolinska Institutet,Karolinska Institute
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- De Faire, Ulf (författare)
- Karolinska Institute
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- Kjellström, Barbro (författare)
- Karolinska Institutet,Karolinska Institute,Lund University,Lunds universitet,Klinisk fysiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Hjärt-MR-gruppen i Lund,Forskargrupper vid Lunds universitet,Clinical Physiology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund Cardiac MR Group,Lund University Research Groups,Skåne University Hospital
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- Klinge, Björn (författare)
- Karolinska Institutet,Malmö University,Karolinska Institute,Malmö universitet,Odontologiska fakulteten (OD),Section of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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- Nygren, Ake (författare)
- Karolinska Inst, Danderyds Hosp, Dept Clin Sci, Stockholm, Sweden.,Department of Clinical Sciences, Danderyds Hospital, Karolinska Institutet, Stockholm, Sweden
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- Näsman, Per, Docent, 1954- (författare)
- KTH Royal Institute of Technology,KTH,Centrum för trafikforskning, CTR,Center for Safety Research, KTH Royal Institute of Technology, Stockholm, Sweden
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- Svenungsson, Elisabet (författare)
- Karolinska Institutet
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- Ryden, Lars (författare)
- Karolinska Institutet,Karolinska Institute
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- Norhammar, Anna (författare)
- Karolinska Institutet,Karolinska Institute,Capio St. Görans Sjukhus
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(creator_code:org_t)
- 2022-08-16
- 2022
- Engelska.
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Ingår i: Scandinavian Cardiovascular Journal. - : Informa UK Limited. - 1401-7431 .- 1651-2006. ; 56:1, s. 337-342
- Relaterad länk:
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https://doi.org/10.1...
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https://mau.diva-por... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Objective. To explore long-term cardiovascular outcomes and mortality in patients after a first myocardial infarction (MI) compared with matched controls in a contemporary setting. Methods. During 2010-2014 the Swedish study PAROKRANK recruited 805 patients <75 years with a first MI and 805 age-, gender-, and area-matched controls. All study participants were followed until 31 December 2018, through linkage with the National Patient Registry and the Cause of Death Registry. The primary endpoint was the first of a composite of all-cause death, non-fatal MI, non-fatal stroke, and heart failure hospitalization. Event rates in cases and controls were calculated using a Cox regression model, subsequently adjusted for baseline smoking, education level, and marital status. Kaplan-Meier curves were computed and compared by log-rank test. Results. A total of 804 patients and 800 controls (mean age 62 years; women 19%) were followed for a mean of 6.2 (0.2-8.5) years. The total number of primary events was 211. Patients had a higher event rate than controls (log-rank test p < .0001). Adjusted hazard ratio (HR) for the primary outcome was 2.04 (95% CI 1.52-2.73). Mortality did not differ between patients (n = 38; 4.7%) and controls (n = 35; 4.4%). A total of 82.5% patients and 91.3% controls were event-free during the follow up. Conclusions. In this long-term follow up of a contemporary, case-control study, the risk for cardiovascular events was higher in patients with a previous first MI compared with their matched controls, while mortality did not differ. The access to high quality of care and cardiac rehabilitation might partly explain the low rates of adverse outcomes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- Cardiovascular prevention
- case-control study
- long-term outcome
- myocardial infarction
- PAROKRANK
- Cardiovascular prevention
- case-control study
- long-term outcome
- myocardial infarction
- PAROKRANK
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Ferrannini, Giul ...
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Almosawi, Mariam
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Buhlin, Kare
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De Faire, Ulf
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Kjellström, Barb ...
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Klinge, Björn
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visa fler...
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Nygren, Ake
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Näsman, Per, Doc ...
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Svenungsson, Eli ...
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Ryden, Lars
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Norhammar, Anna
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Odontologi
- Artiklar i publikationen
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Scandinavian Car ...
- Av lärosätet
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Kungliga Tekniska Högskolan
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Malmö universitet
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Lunds universitet
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Karolinska Institutet