Sökning: WFRF:(Yang Liyun 1992 ) >
Association between...
-
Dong, YidanPeking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth, Beijing, Peoples R China.
(författare)
Association between long-term static postures exposure and musculoskeletal disorders among university employees : A viewpoint of inflammatory pathways
- Artikel/kapitelEngelska2022
Förlag, utgivningsår, omfång ...
-
2022-12-01
-
FRONTIERS MEDIA SA,2022
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:kth-322890
-
https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-322890URI
-
https://doi.org/10.3389/fpubh.2022.1055374DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:151389945URI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
QC 202201111
-
BackgroundMusculoskeletal disorders (MSDs) are critical occupational and social problems. With the improvement of production mechanization and automation, and the widespread application of computers, more occupations are exposed to static postures and load. This study explored the role of inflammation in the association between static postures exposure and MSDs. MethodsThis study adopted a prospective nested case-control design in which 66 lower back MSDs cases and 66 healthy controls were selected from a cohort study of university employees. The personal information, postural load, musculoskeletal symptoms, pressure pain thresholds (PPTs), and inflammatory cytokines were collected. Logistic and linear regressions were used to investigate the association among postural load, inflammatory cytokines, and lower back MSDs. Mediation analysis was used to calculate the mediation effect. ResultsThe results of logistic and linear regressions showed that postural load and inflammatory cytokines were positively associated with lower back MSDs (P < 0.05), and postural load was positively associated with inflammatory cytokines (P < 0.05). Further, mediation analysis showed that the mediation effect of postural load on the lower back MSDs through TNF-alpha was 0.073 (95%CI: 0.025-0.128), and the mediation effect of posture load on the lower back MSDs through IL-6 was 0.098 (95%CI: 0.041-0.179), respectively. ConclusionStatic postures were associated with the occurrence of MSDs through inflammatory cytokines, and low-level inflammation may be a critical early event in the generation of MSDs. This study may help bridge the gap of potential mechanisms linking static postures to increased risks of MSDs, and provide new evidence for targeted protection against the global increasing MSDs.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Jiang, PingPeking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth, Beijing, Peoples R China.
(författare)
-
Jin, XuPeking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth, Beijing, Peoples R China.
(författare)
-
Jiang, NanyuPeking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth, Beijing, Peoples R China.
(författare)
-
Huang, WenchuPeking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth, Beijing, Peoples R China.
(författare)
-
Peng, YuPeking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth, Beijing, Peoples R China.
(författare)
-
Shen, YuhongInst Quartermaster Engn & Technol, Beijing, Peoples R China.
(författare)
-
He, LihuaPeking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth, Beijing, Peoples R China.
(författare)
-
Forsman, Mikael,ProfessorKarolinska Institutet,KTH,Ergonomi,Unit of Occupational Medicine, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden(Swepub:kth)u1iq0ct2
(författare)
-
Yang, Liyun,1992-Karolinska Institutet,KTH,Ergonomi,Unit of Occupational Medicine, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden(Swepub:kth)u1cdwezt
(författare)
-
Peking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth, Beijing, Peoples R China.Inst Quartermaster Engn & Technol, Beijing, Peoples R China.
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Frontiers In Public Health: FRONTIERS MEDIA SA102296-2565
Internetlänk
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Dong, Yidan
-
Jiang, Ping
-
Jin, Xu
-
Jiang, Nanyu
-
Huang, Wenchu
-
Peng, Yu
-
visa fler...
-
Shen, Yuhong
-
He, Lihua
-
Forsman, Mikael, ...
-
Yang, Liyun, 199 ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Hälsovetenskap
-
och Arbetsmedicin oc ...
- Artiklar i publikationen
-
Frontiers In Pub ...
- Av lärosätet
-
Kungliga Tekniska Högskolan
-
Karolinska Institutet