Polydopamine and Magnesium Ions Loaded 3D-Printed Ti-6Al-4V Implants Coating with Enhanced Osteogenesis and Antibacterial Abilities

QC 20230502
3D printing has been applied in the fabrication of Ti-6Al-4V implants due to its high processing efficiency and flexibility. However, the biological inertness of 3D-printed Ti-6Al-4V implant surface limits its further clinical application. This paper aims to improve the biocompatibility of 3D-printed Ti-6Al-4V implants through multi-scale composite structure and bioactive coating. The samples are prepared by selective laser melting (SLM). The multi-scale composite structure is constructed by acid etching and anodic oxidation, and then the bioactive coating is added by hydrothermal treatment. The results indicate that acid etching removes the residuals on the surface and builds micron-/sub-micron structures. Anodic oxidation superimposes TiO2 nanotube arrays with a diameter of ≈80 nm, forming the multi-scale composite structure. The polydopamine-magnesium ion coating is added by hydrothermal treatment on the basis of retaining the multi-scale composite structure. After modification, the surface wettability and corrosion resistance are improved, and the roughness is slightly reduced. Regarding the biocompatibility of the modified 3D-printed Ti-6Al-4V implant, its admirable osteogenic induction performance is verified on osteoblasts (MC3T3-E1). Also, the addition of magnesium ions achieves better antibacterial properties. The results provide new target points for the surface modification of 3D-printed Ti-6Al-4V implant to attain better clinical performance.

TEKNIK OCH TEKNOLOGIER Materialteknik Annan materialteknik hsv//swe
ENGINEERING AND TECHNOLOGY Materials Engineering Other Materials Engineering hsv//eng
3D-printed Ti-6Al-4V implants
biocompatibility
magnesium ions
multi-scale composite structures
polydopamine
3D printers
Aluminum alloys
Aluminum coatings
Anodic oxidation
Corrosion resistance
Etching
Magnesium
Metal implants
Metal ions
Structure (composition)
Ternary alloys
Titanium alloys
Titanium dioxide
Vanadium alloys
3d-printed ti-6al-4v implant
Acid-etching
Bioactive coatings
Composites structures
Hydrothermal treatments
Multi-scale composite structure
Multi-scale composites
Osteogenesis

By the author/editor: Ji, Z.; Wan, Y.; Zhao, Z.; Wang, Teng; Yu, M.; Wang, H.; show more...; Fan, S.; Liu, Z.; Liu, C.; show less...

About the subject

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Materials Engine ...; and Other Materials ...

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