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Elucidating tricusp...
Elucidating tricuspid Doppler signal interpolation and its implication for assessing pulmonary hypertension
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- Dual, Seraina A., 1991- (författare)
- Department of Cardiothoracic Surgery Stanford University School of Medicine Stanford California USA;Cardiovascular Institute Stanford University Stanford California USA
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- Verdonk, Constance (författare)
- Department of Medicine, Division of Cardiovascular Medicine Stanford University School of Medicine Stanford California USA;Department of Cardiothoracic Surgery Hospital Bichat Paris France;INSERM U1148, Cardiovascular Bioengineering Paris France
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- Amsallem, Myriam (författare)
- Cardiovascular Institute Stanford University Stanford California USA;Department of Medicine, Division of Cardiovascular Medicine Stanford University School of Medicine Stanford California USA;KU Leuven Department of Cardiovascular Sciences, Research Unit Hypertension and Cardiovascular Epidemiology University of Leuven Leuven Belgium
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- Pham, Jonathan (författare)
- Department of Pediatrics Division of Pediatric Cardiology, Stanford University School of Medicine Palo Alto California USA;Department of Bioengineering Stanford University School of Medicine Stanford California USA
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- Obasohan, Courtney (författare)
- Department of Medicine Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine Stanford California USA
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- Nataf, Patrick (författare)
- Department of Cardiothoracic Surgery Hospital Bichat Paris France;INSERM U1148, Cardiovascular Bioengineering Paris France
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- McElhinney, Doff B. (författare)
- Department of Cardiothoracic Surgery Stanford University School of Medicine Stanford California USA;Cardiovascular Institute Stanford University Stanford California USA
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- Arunamata, Alisa (författare)
- Department of Pediatrics Division of Pediatric Cardiology, Stanford University School of Medicine Palo Alto California USA
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- Kuznetsova, Tatiana (författare)
- KU Leuven Department of Cardiovascular Sciences, Research Unit Hypertension and Cardiovascular Epidemiology University of Leuven Leuven Belgium
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- Zamanian, Roham (författare)
- Department of Mechanical Engineering Stanford University California Stanford USA;Vera Moulton Wall Center for Pulmonary Vascular Disease at Stanford Stanford California USA
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- Feinstein, Jeffrey A. (författare)
- Department of Pediatrics Division of Pediatric Cardiology, Stanford University School of Medicine Palo Alto California USA;Department of Bioengineering Stanford University School of Medicine Stanford California USA;Department of Mechanical Engineering Stanford University California Stanford USA
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- Marsden, Alison (författare)
- Cardiovascular Institute Stanford University Stanford California USA;Department of Pediatrics Division of Pediatric Cardiology, Stanford University School of Medicine Palo Alto California USA;Department of Bioengineering Stanford University School of Medicine Stanford California USA;Department of Mechanical Engineering Stanford University California Stanford USA
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- Haddad, François (författare)
- Cardiovascular Institute Stanford University Stanford California USA;Department of Medicine, Division of Cardiovascular Medicine Stanford University School of Medicine Stanford California USA
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(creator_code:org_t)
- 2022-08-22
- 2022
- Engelska.
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Ingår i: Pulmonary Circulation. - : Wiley. - 2045-8932 .- 2045-8940. ; 12:3, s. e12125-
- Relaterad länk:
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https://doi.org/10.1...
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https://kth.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Doppler echocardiography plays a central role in the assessment of pulmonary hypertension (PAH). We aim to improve quality assessment of systolic pulmonary arterial pressure (SPAP) by applying a cubic polynomial interpolation to digitized tricuspid regurgitation (TR) waveforms. Patients with PAH and advanced lung disease were divided into three cohorts: a derivation cohort (n = 44), a validation cohort (n = 71), an outlier cohort (n = 26), and a non-PAH cohort (n = 44). We digitized TR waveforms and analyzed normalized duration, skewness, kurtosis, and first and second derivatives of pressure. Cubic polynomial interpolation was applied to three physiology-driven phases: the isovolumic phase, ejection phase, and “shoulder” point phase. Coefficients of determination and a Bland−Altman analysis was used to assess bias between methods. The cubic polynomial interpolation of the TR waveform correlated strongly with expert read right ventricular systolic pressure (RVSP) with R2 > 0.910 in the validation cohort. The biases when compared to invasive SPAP measured within 24 h were 6.03 [4.33; 7.73], −2.94 [1.47; 4.41], and −3.11 [−4.52; −1.71] mmHg, for isovolumic, ejection, and shoulder point interpolations, respectively. In the outlier cohort with more than 30% difference between echocardiographic estimates and invasive SPAP, cubic polynomial interpolation significantly reduced underestimation of RVSP. Cubic polynomial interpolation of the TR waveform based on isovolumic or early ejection phase may improve RVSP estimates.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Image Processing (hsv//eng)
Nyckelord
- pulmonary hypertension
- ultrasound
- Doppler
- Medical Technology
- Medicinsk teknologi
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- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Dual, Seraina A. ...
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Verdonk, Constan ...
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Amsallem, Myriam
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Pham, Jonathan
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Obasohan, Courtn ...
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Nataf, Patrick
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visa fler...
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McElhinney, Doff ...
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Arunamata, Alisa
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Kuznetsova, Tati ...
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Zamanian, Roham
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Feinstein, Jeffr ...
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Marsden, Alison
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Haddad, François
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visa färre...
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- TEKNIK OCH TEKNOLOGIER
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TEKNIK OCH TEKNO ...
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Pulmonary Circul ...
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