The mechanical bond in biological systems

Sökning: L773:2451 9294 > The mechanical bond...

Beeren, Sophie R.Tech Univ Denmark, Dept Chem, Kemitorvet Bldg 207, DK-2800 Lyngby, Denmark. (författare)

QC 20230722
The field of mechanically interlocked molecules (MIMs) has advanced rapidly in recent years, with much work focused on their use in materials, sensing, and catalysis. However, the use of MIMs in biology and biomedicine has been limited, despite the identifica-tion of naturally occurring MIMs in DNA and proteins and the poten-tial advantages of the mechanical bond in fields such as nanomedi-cine and tissue engineering. Difficulties in the synthesis of MIMs, along with their limited solubility and stability in biological media, have until recently impeded their wider application in biology. Contemporary advances have, however, enabled a broader integra-tion of the mechanical bond in biology; the mechanical interlocking endows these systems with unique functional advantages. Herein, we summarize recent advances in the application of small-molecule, biologically derived, and polymeric MIMs in biology, highlighting synergies ripe for future exploration.

McTernan, Charlie T.Francis Crick Inst, Artificial Mol Machinery Lab, 1 Midland Rd, London NW1 1AT, England.;Kings Coll London, Dept Chem, Britannia House,7 Trinity St, London SE1 1DB, England. (författare)
Schaufelberger, FredrikKTH,Organisk kemi(Swepub:kth)u1w7xjb6 (författare)
Tech Univ Denmark, Dept Chem, Kemitorvet Bldg 207, DK-2800 Lyngby, Denmark.Francis Crick Inst, Artificial Mol Machinery Lab, 1 Midland Rd, London NW1 1AT, England.;Kings Coll London, Dept Chem, Britannia House,7 Trinity St, London SE1 1DB, England. (creator_code:org_t)

Av författaren/redakt...: Beeren, Sophie R ...; McTernan, Charli ...; Schaufelberger, ...

Om ämnet

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.