Hepatic hemangiomas: diagnosis with fusion of MR, CT, and Tc-99m-labeled red blood cell SPECT images

QC 20111107. PMID: 1924790
A method of image analysis was developed for correlation of hemangiomas detected at computed tomography {(CT)} and/or magnetic resonance {(MR)} imaging with increased blood pool activity evident at single photon emission {CT} {(SPECT)} performed after labeling of red blood cells with technetium-99m. Image analysis was performed in 20 patients with 35 known hepatic hemangiomas. After section thickness and pixel sizes of the different studies were matched, intrinsic landmarks were chosen to identify anatomically corresponding locations. Regions of interest {(ROIs)} drawn on the {CT} and/or {MR} images were translated, rotated, and reprojected to match the areas of interest on the corresponding {SPECT} images by means of a two-dimensional polynomial-based warping algorithm. Analysis of {ROIs} on 30 {SPECT-MR} and 20 {SPECT-CT} pairs of registered images provided absolute confirmation that 34 suspected hemangiomas identified on {SPECT} images correlated exactly with lesions seen on {CT} and/or {MR} images. Accuracy of fusion was within an average of 1.5 pixels +/- 0.8 (+/- 1 standard deviation). The technique enabled diagnostic confirmation of hemangiomas as small as 1.0 cm and proved useful for evaluating lesions located adjacent to intrahepatic vessels.

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
Adult
Aged
Erythrocytes
Female
Hemangioma
Humans
Image Processing
{Computer-Assisted}
Liver
Liver Neoplasms
Magnetic Resonance Imaging
Male
Middle Aged
Tomography
{Emission-Computed}
{Single-Photon}
Tomography
{X-Ray} Computed
SRA - ICT
SRA - Informations- och kommunikationsteknik

Noz, Marilyn E.New York University (författare)
Chapnick, Jeffrey V.New York University (författare)
Sanger, Joseph J.New York University (författare)
Megibow, Alec J.New York University (författare)
Maguire Jr., Gerald Q.Columbia University, Department of Computer Science(Swepub:kth)u1d13i2c (författare)
Weinreb, Jeffrey C.New York University (författare)
Kaminer, Evan M.New York University (författare)
Kramer, Elissa L.New York University (författare)
New York UniversityColumbia University, Department of Computer Science (creator_code:org_t)

Ingår i:Radiology: Radiological Society of North America181:2, s. 469-4740033-84191527-1315

Av författaren/redakt...: Birnbaum, Bernar ...; Noz, Marilyn E.; Chapnick, Jeffre ...; Sanger, Joseph J ...; Megibow, Alec J.; Maguire Jr., Ger ...; visa fler...; Weinreb, Jeffrey ...; Kaminer, Evan M.; Kramer, Elissa L ...; visa färre...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Radiologi och bi ...

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