A high-performance magnetic resonance imaging T2 contrast agent

• A high-performance magnetic resonance imaging T-2 contrast agent has been prepared via phase transfer of hydrophobic superparamagnetic iron oxide nanoparticles (SPIONs) to an aqueous solution by using Pluronic F127 copolymers. As seen in the figure, a hierarchical structure of the surface coating is formed and proven to be a crucial characteristic to enhance not only water dispersibility, but also the efficacy as a T-2 contrast agent.

Nyckelord

superparamagnetic iron-oxide

aqueous-solutions

block-copolymers

nanocrystals

nanoparticles

water

mri

size

micelles

media

TECHNOLOGY

TEKNIKVETENSKAP

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