CELL 28-Biointeractive fibers with antibacterial properties

• Growth of bacteria on various surfaces may cause major concern if encountered in the wrong environment.  The ability to impart antimicrobial properties onto surfaces is therefore desirable.  Modification of both glass surfaces and cellulose membranes using weak polyelectrolytes as antimicrobial agent is presented.  The aim was to incorporate a known carrier of antimicrobial activity into a multilayer structure of adsorbed polyelectolytes at different surfaces and evaluate the antibacterial activities.  The approach involved screening for antimicrobial activity in soln. of modified and unmodified polymers.  The polymers were evaluated against gram-neg. E. coli and gram-pos. B. subtilis. In order to elucidate the mode of action of the polymers, the charge was detd.  This is done since earlier studies have shown that both charge and degree of hydrophobicity are of importance in terms of exerted activity.  Results show that the chosen polymers exert activity in the immobilized state.  Different techniques have been used to evaluate the mechanisms.

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Kemiteknik -- Polymerteknologi (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Chemical Engineering -- Polymer Technologies (hsv//eng)

NATURVETENSKAP  -- Kemi -- Polymerkemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Polymer Chemistry (hsv//eng)

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