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Early clinical outc...
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Ihlberg, LeoHelsinki University Hospital, Finland
(författare)
Early clinical outcome of aortic transcatheter valve-in-valve implantation in the Nordic countries
- Artikel/kapitelEngelska2013
Förlag, utgivningsår, omfång ...
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Elsevier,2013
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-100475
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-100475URI
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https://doi.org/10.1016/j.jtcvs.2013.06.045DOI
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https://lup.lub.lu.se/record/4160332URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:127557253URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Objective: Transcatheter valve-in-valve implantation has emerged as an option, in addition to reoperative surgical aortic valve replacement, to treat failed biologic heart valve substitutes. However, the clinical experience with this approach is still limited. We report the comprehensive experience of transcatheter valve-in-valve implantation in the Nordic countries from May 2008 to January 2012. less thanbrgreater than less thanbrgreater thanMethods: A total of 45 transcatheter aortic valve-in-valve implantations were performed during the study period in 11 centers. The mean age of the patients was 80.6 years (range, 61-91), 26 were male and 19 were female, and the mean EuroSCORE, EuroSCORE II, and Society of Thoracic Surgeons score was 35.4, 16.3, and 14.6, respectively. The type of failure was stenosis and combined in 58% (mean and peak aortic valve gradient, 77 and 45 mm Hg, respectively) and regurgitation in 42% of cases. The SAPIEN/XT (Edwards LifeSciences, Irvine, Calif) and CoreValve (Medtronic Inc, Minneapolis, Minn) system was used in 33 and 12 cases, respectively. The access route was transapical in 25, transfemoral in 17, transaortic in 2, and subclavian in 1 case. The mean follow-up was 14.4 months. The periprocedural and postoperative outcomes were assessed using the Valve Academic Research Consortium criteria. less thanbrgreater than less thanbrgreater thanResults: No intraprocedural mortality occurred. The technical success rate was 95.6% (1 second valve implantation, 1 conversion to open surgery). The all-cause 30-day mortality was 4.4% (1 cardiac-related and 1 aspiration pneumonia). The major complications within 30 days included stroke in 2.2%, periprocedural myocardial infarction in 4.4%, and major vascular complication in 2.2% of patients. At 1 month, all but 1 patient had either no or mild paravalvular leakage, with a mean and peak valve gradient of 17 mm Hg (range, 4-38) and 30 mm Hg (range, 7-68), respectively. The mean gradient was greater than 20 mm Hg in 17% of patients and remained unchanged at 12 months. The 1-year survival was 88.1%. less thanbrgreater than less thanbrgreater thanConclusions: Transcatheter valve-in-valve implantation is widely performed, albeit in small numbers, in most centers in the Nordic countries. The short-termresults were excellent in this high-risk patient population, demonstrating a low incidence of device-or procedure-related complications. However, a considerable number of patients were left with suboptimal systolic valve performance with unknown long-term effects, warranting close surveillance after transcatheter valve-in-valve implantation.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Nissen, HenrikOdense University Hospital, Denmark
(författare)
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Nielsen, Niels ErikÖstergötlands Läns Landsting,Linköpings universitet,Kardiologi,Hälsouniversitetet,Kardiologiska kliniken US(Swepub:liu)nieni36
(författare)
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Rueck, AndreasKarolinska Institutet,Karolinska University Hospital, Sweden
(författare)
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Busund, RolfUniversity Hospital North Norway, Norway
(författare)
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Klaarborg, Kaj-ErikAarhus University Hospital, Denmark
(författare)
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Soendergaard, LarsRigshosp, Denmark
(författare)
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Harnek, JanLund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,University of Lund Hospital, Sweden(Swepub:lu)drad-jha
(författare)
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Miettinen, HeikkiKuopio University Hospital, Finland
(författare)
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Eskola, MarkkuTampere University Hospital, Finland
(författare)
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Wahba, AlexanderNorwegian University of Science and Technology, Norway
(författare)
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Laine, MikaHelsinki University Hospital, Finland
(författare)
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Helsinki University Hospital, FinlandOdense University Hospital, Denmark
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Thoracic and Cardiovascular Surgery: Elsevier146:5, s. 1047-10540022-52231097-685X
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Ihlberg, Leo
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Nissen, Henrik
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Nielsen, Niels E ...
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Rueck, Andreas
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Busund, Rolf
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Klaarborg, Kaj-E ...
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visa fler...
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Soendergaard, La ...
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Harnek, Jan
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Miettinen, Heikk ...
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Eskola, Markku
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Wahba, Alexander
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Laine, Mika
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- MEDICIN OCH HÄLSOVETENSKAP
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och Klinisk medicin
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och Kardiologi
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
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Linköpings universitet
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Lunds universitet
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Karolinska Institutet