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  • Duan, MaoliKarolinska Institutet (author)

Imaging of the guinea pig cochlea following round window gadolinium application

  • Article/chapterEnglish2004

Publisher, publication year, extent ...

  • Wolters Kluwer,2004
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-101072
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-101072URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-37175URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:1937939URI
  • https://doi.org/10.1097/00001756-200408260-00019DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Precise, non-invasive determination of the aetiology and site of pathology of inner ear disorders is difficult. The aim of this study was to describe an alternative method for inner ear visualization, based on local application of the paramagnetic contrast agent gadolinium. Using a 4.7 T MRI scanner, high contrast images of all four cochlear turns were obtained 3.5 h after placing gadolinium on the round window membrane. Gadolinium cleared from the cochlea within 96 h. Auditory brainstem response measurements performed on a separate group of animals showed no significant threshold shifts after the application, indicating that gadolinium is non-toxic to the guinea pig cochlea.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Bjelke, BörjeÖrebro University Hospital, Sweden,Department of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden (author)
  • Fridberger, Anders,1966-Karolinska Institutet(Swepub:liu)andfr39 (author)
  • Counter, AllenDepartment of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden (author)
  • Klason, TomasDepartment of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden (author)
  • Skjönsberg, ÅsaKarolinska Institutet (author)
  • Herrlin, PetraKarolinska Institutet (author)
  • Borg, ErikAhlsen Research Institute, Örebro University Hospital, 701 85 Örebro, Sweden (author)
  • Laurell, GöranKarolinska Institutet(Swepub:umu)gala0001 (author)
  • Karolinska InstitutetÖrebro University Hospital, Sweden (creator_code:org_t)

Related titles

  • In:NeuroReport: Wolters Kluwer15:12, s. 1927-19300959-49651473-558X

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