Clinical Utility of Cognistat in Multiprofessional Team Evalutations of Patients with Cognitive Impairment in Swedish Primary Care

Johansson, MariaÖstergötlands Läns Landsting,Linköpings universitet,Avdelningen för neurovetenskap,Hälsouniversitetet,Neurologiska kliniken (författare)

Background. Diagnostic evaluations of dementia are often performed in primary health care (PHC). Cognitive evaluation requires validated instruments.Objective. To investigate the diagnostic accuracy and clinical utility of Cognistat in a primary care population.Methods. Participants were recruited from 4 PHC centres; 52 had cognitive symptoms and 29 were presumed cognitively healthy. Participants were tested using the Mini-Mental State Examination (MMSE), the Clock Drawing Test (CDT), and Cognistat. Clinical diagnoses, based on independent neuropsychological examination and a medical consensus discussion in secondary care, were used as criteria for diagnostic accuracy analyses.Results. The sensitivity, specificity, positive predictive value, and negative predictive value were 0.85, 0.79, 0.85, and 0.79, respectively, for Cognistat; 0.59, 0.91, 0.90, and 0.61 for MMSE; 0.26, 0.88, 0.75, and 0.46 for CDT; 0.70, 0.79, 0.82, and 0.65 for MMSE and CDT combined. The area under the receiver operating characteristic curve was 0.82 for Cognistat, 0.75 for MMSE, 0.57 for CDT, and 0.74 for MMSE and CDT combined.Conclusions. The diagnostic accuracy and clinical utility of Cognistat was better than the other tests alone or combined. Cognistat is well adapted for cognitive evaluations in PHC and can help the general practitioner to decide which patients should be referred to secondary care.

Segernäs Kvitting, AnnaÖstergötlands Läns Landsting,Linköpings universitet,Avdelningen för samhällsmedicin,Hälsouniversitetet,Primärvården i centrala länsdelen(Swepub:liu)annse67 (författare)
Wressle, EwaÖstergötlands Läns Landsting,Linköpings universitet,Avdelningen för neurovetenskap,Hälsouniversitetet,Geriatriska kliniken(Swepub:liu)ewawr36 (författare)
Marcusson, JanÖstergötlands Läns Landsting,Linköpings universitet,Avdelningen för neurovetenskap,Hälsouniversitetet,Geriatriska kliniken(Swepub:liu)janma25 (författare)
Linköpings universitetAvdelningen för neurovetenskap (creator_code:org_t)

Ingår i:International Journal of Family Medicine: Hindawi Publishing Corporation2014, s. 649253-2090-20422090-2050

Av författaren/redakt...: Johansson, Maria; Segernäs Kvittin ...; Wressle, Ewa; Marcusson, Jan

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