Sökning: WFRF:(Goldis A) >
East-West gradient ...
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Burisch, J.Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark
(författare)
East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort
- Artikel/kapitelEngelska2014
Förlag, utgivningsår, omfång ...
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2013-04-20
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BMJ Publishing Group,2014
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-107459
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-107459URI
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https://doi.org/10.1136/gutjnl-2013-304636DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-36004URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:128984961URI
Kompletterande språkuppgifter
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Språk:engelska
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Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Objective The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe. The reasons for these changes remain unknown. The aim of this study was to investigate whether an East–West gradient in the incidence of IBD in Europe exists.Design A prospective, uniformly diagnosed, population based inception cohort of IBD patients in 31 centres from 14 Western and eight Eastern European countries covering a total background population of approximately 10.1 million people was created. One-third of the centres had previous experience with inception cohorts. Patients were entered into a low cost, web based epidemiological database, making participation possible regardless of socioeconomic status and prior experience.Results 1515 patients aged 15 years or older were included, of whom 535 (35%) were diagnosed with Crohn's disease (CD), 813 (54%) with ulcerative colitis (UC) and 167 (11%) with IBD unclassified (IBDU). The overall incidence rate ratios in all Western European centres were 1.9 (95% CI 1.5 to 2.4) for CD and 2.1 (95% CI 1.8 to 2.6) for UC compared with Eastern European centres. The median crude annual incidence rates per 100 000 in 2010 for CD were 6.5 (range 0–10.7) in Western European centres and 3.1 (range 0.4–11.5) in Eastern European centres, for UC 10.8 (range 2.9–31.5) and 4.1 (range 2.4–10.3), respectively, and for IBDU 1.9 (range 0–39.4) and 0 (range 0–1.2), respectively. In Western Europe, 92% of CD, 78% of UC and 74% of IBDU patients had a colonoscopy performed as the diagnostic procedure compared with 90%, 100% and 96%, respectively, in Eastern Europe. 8% of CD and 1% of UC patients in both regions underwent surgery within the first 3 months of the onset of disease. 7% of CD patients and 3% of UC patients from Western Europe received biological treatment as rescue therapy. Of all European CD patients, 20% received only 5-aminosalicylates as induction therapy.Conclusions An East–West gradient in IBD incidence exists in Europe. Among this inception cohort—including indolent and aggressive cases—international guidelines for diagnosis and initial treatment are not being followed uniformly by physicians.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Pedersen, N.Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark
(författare)
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Cukovic-Cavka, S.Division of Gastroenterology and Hepatology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia,Hull and East Yorkshire NHS Trust and Hull and York Medical School, Hull Royal Infirmary, Hull, UK,Hull and E Yorkshire NHS Trust and Hull and York, England
(författare)
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Brinar, M.Division of Gastroenterology and Hepatology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia
(författare)
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Kaimakliotis, I.Nicosia private practice, Nicosia, Cyprus
(författare)
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Duricova, D.Charles University of Prague, Czech Republic,IBD Centre ISCARE, Charles University, Prague, Czech Republic,Department of Gastroenterology and Hepatology, Soroka Medical Centre and Ben Gurion University of the Negev, Beer Sheva, Israel,UO Gastroenterologia, Azienda Ospedaliera-Università di Padova, Padova, Italy,Clinic of Gastroenterology, University of Medicine ‘Victor Babes’, Timisoara, Romania,Gastroenterology Department, Complexo Hospitalario Universitario de Vigo, Vigo, Spain,University of Medical Victor Babes, Romania,Complexo Hospital University of Vigo, Spain
(författare)
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Shonova, O.Gastroenterology Department, Hospital České Budějovice, České Budějovice, Czech Republic,Department of Gastroenterology and Hepatology, Soroka Medical Centre and Ben Gurion University of the Negev, Beer Sheva, Israel
(författare)
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Vind, I.Department of Medicine, Amager Hospital, Amager, Denmark
(författare)
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Avnstrom, S.Department of Medicine, Amager Hospital, Amager, Denmark
(författare)
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Thorsgaard, N.Department of Medicine, Herning Central Hospital, Herning, Denmark
(författare)
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Andersen, V.Medical Department, Viborg Regional Hospital, Viborg, Denmark; Medical Department, Hospital of Southern Jutland, Aabenraa, Denmark; University of Southern Denmark, Odense, Denmark
(författare)
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Krabbe, S.Medical Department, Viborg Regional Hospital, Viborg, Denmark
(författare)
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Dahlerup, J.F.Department of Medicine V (Hepatology and Gastroenterology), Aarhus University Hospital, Arhus, Denmark
(författare)
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Salupere, R.Division of Endocrinology and Gastroenterology, Tartu University Hospital, Tartu, Estonia
(författare)
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Nielsen, K.R.National Hospital Faroe Isl, Denmark,Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands
(författare)
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Olsen, J.National Hospital Faroe Isl, Denmark,Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands
(författare)
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Manninen, P.Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland
(författare)
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Collin, P.Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland
(författare)
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Tsianos, E.V.1st Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece
(författare)
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Katsanos, K.H.1st Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece
(författare)
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Ladefoged, K.Medical Department, Dronning Ingrids Hospital, Nuuk, Greenland,Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania,Az Osped Osped Cremona, Italy Lithuanian University of Health Science, Lithuania
(författare)
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Lakatos, L.1st Department of Medicine, Semmelweis University, Budapest, Hungary,Hospital de Vale de Sousa, Porto, Portugal
(författare)
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Bjornsson, E.Department of Internal Medicine, Section of Gastroenterology and Hepatology, The National University Hospital, Reykjavik, Iceland
(författare)
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Ragnarsson, G.Department of Internal Medicine, Section of Gastroenterology and Hepatology, The National University Hospital, Reykjavik, Iceland
(författare)
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Bailey, Y.Department of Gastroenterology, Adelaide and Meath Hospital, TCD, Dublin, Ireland
(författare)
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Odes, S.Ben Gurion University of Negev, Israel Ben Gurion University of Negev, Israel
(författare)
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Schwartz, D.Ben Gurion University of Negev, Israel Ben Gurion University of Negev, Israel
(författare)
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Martinato, M.UO Gastroenterologia, Azienda Ospedaliera—Università di Padova, Padova, Italy,Gastroenterology Unit, Careggi Hospital, Florence, Italy,UO Gastroenterologia ed Endoscopia Digestiva, Ospedale Morgagni-Pierantoni, Forlì, Italy,Azienda Osped Arcispedale S Maria Nuova, Italy
(författare)
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Lupinacci, G.UO Gastroenterol Endoscopia Digest, Italy,UO di Medicina e Gastroenterologia, Az Ospedaliera Ospedale di Cremona, Cremona, Italy; UO di Gastroenterologia e Endoscopia Digestiva, Az Ospedaliera Ospedale Maggiore di Crema, Crema, Italy
(författare)
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Milla, M.Careggi Hospital, Italy
(författare)
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De Padova, A.Osped Morgagni Pierantoni, Italy,UO Gastroenterologia ed Endoscopia Digestiva, Ospedale Morgagni-Pierantoni, Forlì, Italy
(författare)
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D'lnca, R.Azienda Ospedaliera—Università di Padova, Padova, Italy
(författare)
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Beltrami, M.Azienda Osped Arcispedale S Maria Nuova, Italy
(författare)
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Kupcinskas, L.Az Osped Osped Cremona, Italy Lithuanian University of Health Science, Lithuania
(författare)
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Kiudelis, G.Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania
(författare)
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Turcan, S.Department of Gastroenterology, State University of Medicine and Pharmacy of the Republic of Moldova, Chisinau, Republic of Moldova
(författare)
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Tighineanu, O.Department of Paediatric Gastroenterology, Centre of Mother and Child, Chisinau, Republic of Moldova
(författare)
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Mihu, I.Department of Paediatric Gastroenterology, Centre of Mother and Child, Chisinau, Republic of Moldova
(författare)
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Magro, F.Hospital Sao Joao, Portugal Oporto Medical Sch, Portugal University of Porto, Portugal,Department of Gastroenterology, Hospital de São João, Porto, Portugal; Institute of Pharmacology and Therapeutics, Oporto Medical School, Porto, Portugal; Hospital de Vale de Sousa, Porto, Portugal
(författare)
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Barros, L.F.Hospital Vale Sousa, Portugal
(författare)
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Goldis, A.University of Medical Victor Babes, Romania,Clinic of Gastroenterology, University of Medicine ‘Victor Babes’, Timisoara, Romania
(författare)
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Lazar, D.University of Medical Victor Babes, Romania
(författare)
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Belousova, E.Moscow Regional Research Clin Institute, Russia,Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russia
(författare)
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Nikulina, I.Moscow Regional Research Clin Institute, Russia,Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russia
(författare)
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Hernandez, V.Complexo Hospital University of Vigo, Spain,Gastroenterology Department, Complexo Hospitalario Universitario de Vigo, Vigo, Spain
(författare)
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Martinez-Ares, D.Complexo Hospital University of Vigo, Spain
(författare)
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Almer, SvenKarolinska Institutet,Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för inflammationsmedicin,Hälsouniversitetet,Magtarmmedicinska kliniken,Division of Gastroenterology and Hepatology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden; Department of Gastroenterology/UHL, County Council of Östergötland, Linköping, Sweden(Swepub:liu)sveal38
(författare)
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Zhulina, Yaroslava,1973-Region Örebro län,Department of Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden(Swepub:oru)yza
(författare)
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Halfvarson, Jonas,1970-Region Örebro län,Örebro universitet, Institutionen för hälsovetenskap och medicin,Department of Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden(Swepub:oru)jshn
(författare)
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Arebi, N.University of London Imperial Coll Science Technology and Med, England,Sir Alan Park's Physiology Unit, St Mark's Hospital, Imperial College London, London, UK
(författare)
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Sebastian, S.Hull and E Yorkshire NHS Trust and Hull and York, England
(författare)
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Lakatos, P.L.Semmelweis University, Budapest, Hungary
(författare)
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Langholz, E.Gentofte University Hospital, Denmark,Department of Medical Gastroenterology, Gentofte Hospital, Copenhagen, Denmark
(författare)
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Munkholm, P.Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark
(författare)
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Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, DenmarkDivision of Gastroenterology and Hepatology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Gut: BMJ Publishing Group63:4, s. 588-5970017-57491468-3288
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Till lärosätets databas
- Av författaren/redakt...
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Burisch, J.
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Pedersen, N.
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Cukovic-Cavka, S ...
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Brinar, M.
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Kaimakliotis, I.
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Duricova, D.
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visa fler...
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Shonova, O.
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Vind, I.
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Avnstrom, S.
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Thorsgaard, N.
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Andersen, V.
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Krabbe, S.
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Dahlerup, J.F.
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Salupere, R.
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Nielsen, K.R.
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Olsen, J.
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Manninen, P.
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Collin, P.
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Tsianos, E.V.
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Katsanos, K.H.
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Ladefoged, K.
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Lakatos, L.
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Bjornsson, E.
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Ragnarsson, G.
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Bailey, Y.
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Odes, S.
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Schwartz, D.
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Martinato, M.
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Lupinacci, G.
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Milla, M.
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De Padova, A.
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D'lnca, R.
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Beltrami, M.
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Kupcinskas, L.
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Kiudelis, G.
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Turcan, S.
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Tighineanu, O.
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Mihu, I.
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Magro, F.
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Barros, L.F.
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Goldis, A.
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Lazar, D.
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Belousova, E.
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Nikulina, I.
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Hernandez, V.
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Martinez-Ares, D ...
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Almer, Sven
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Zhulina, Yarosla ...
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Halfvarson, Jona ...
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Arebi, N.
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Sebastian, S.
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Lakatos, P.L.
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Langholz, E.
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Munkholm, P.
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visa färre...
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Linköpings universitet
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Örebro universitet
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Karolinska Institutet