Sökning: id:"swepub:oai:DiVA.org:liu-108174" >
Vitamin D deficienc...
-
Samefors, MariaLinköpings universitet,Avdelningen för samhällsmedicin,Hälsouniversitetet
(författare)
Vitamin D deficiency in elderly people in Swedish nursing homes is associated with increased mortality
- Artikel/kapitelEngelska2014
Förlag, utgivningsår, omfång ...
-
Bioscientifica,2014
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:liu-108174
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-108174URI
-
https://doi.org/10.1530/EJE-13-0855DOI
-
https://lup.lub.lu.se/record/4558472URI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
OBJECTIVE:Institutionalised elderly people at northern latitudes may be at elevated risk for vitamin D deficiency. In addition to osteoporosis-related disorders, vitamin D deficiency may influence several medical conditions conferring an increased mortality risk. The aim of this study was to explore the prevalence of vitamin D deficiency and its association with mortality.DESIGN:The Study of Health and Drugs in the Elderly (SHADES) is a prospective cohort study among elderly people (>65 years) in 11 nursing homes in Sweden.METHODS:We analysed the levels of 25-hydroxyvitamin D₃ (25(OH)D₃) at baseline. Vital status of the subjects was ascertained and hazard ratios (HRs) for mortality according to 25(OH)D₃ quartiles were calculated.RESULTS:We examined 333 study participants with a mean follow-up of 3 years. A total of 147 (44%) patients died within this period. Compared with the subjects in Q4 (25(OH)D₃ >48 nmol/l), HR (with 95% CI) for mortality was 2.02 (1.31-3.12) in Q1 (25(OH)D₃ <29 nmol/l) (P<0.05); 2.03 (1.32-3.14) in Q2 (25(OH)D₃ 30-37 nmol/l) (P<0.05) and 1.6 (1.03-2.48) in Q3 (25(OH)D₃ 38-47 nmol/l) (P<0.05). The mean 25(OH)D₃ concentration was 40.2 nmol/l (S.D. 16.0) and 80% had 25(OH)D₃ below 50 nmol/l. The vitamin D levels decreased from baseline to the second and third measurements.CONCLUSIONS:Vitamin D deficiency was highly prevalent and associated with increased mortality among the elderly in Swedish nursing homes. Strategies are needed to prevent, and maybe treat, vitamin D deficiency in the elderly in nursing homes and the benefit of vitamin D supplementation should be evaluated in randomised clinical trials.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Östgren, Carl JohanÖstergötlands Läns Landsting,Linköpings universitet,Avdelningen för samhällsmedicin,Hälsouniversitetet,Primärvården i västra länsdelen(Swepub:liu)caros18
(författare)
-
Mölstad, SigvardLund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Lund University, Malmö, Sweden(Swepub:lu)med-sm2
(författare)
-
Lannering, ChristinaFuturum, Jönköping, Sweden
(författare)
-
Midlöv, PatrikLund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Lund University, Malmö, Sweden(Swepub:lu)klin-pmi
(författare)
-
Tengblad, AndersFuturum, Jönköping, Sweden
(författare)
-
Linköpings universitetAvdelningen för samhällsmedicin
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:European Journal of Endocrinology: Bioscientifica170:5, s. 667-6750804-46431479-683X
Internetlänk
Hitta via bibliotek
Till lärosätets databas