CONTRAIS: CONservative TReatment for Adolescent Idiopathic Scoliosis: a randomised controlled trial protocol

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Abbott, AllanKarolinska Institutet,Karolinska Institutet, Stockholm, Sweden; Karolinska University Hospital, Stockholm, Sweden; Bond University, Gold Coast, Australia (författare)

CONTRAIS: CONservative TReatment for Adolescent Idiopathic Scoliosis : a randomised controlled trial protocol

Artikel/kapitelEngelska2013

Förlag, utgivningsår, omfång ...

2013-09-05
BioMed Central,2013
printrdacarrier

Nummerbeteckningar

LIBRIS-ID:oai:DiVA.org:liu-114059
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-114059URI
https://doi.org/10.1186/1471-2474-14-261DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:127335807URI

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Språk:engelska
Sammanfattning på:engelska

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Anmärkningar

Background:Idiopathic scoliosis is a three-dimensional structural deformity of the spine that occurs in children and adolescents. Recent reviews on bracing and exercise treatment have provided some evidence for effect of these interventions. The purpose of this study is to improve the evidence base regarding the effectiveness of conservative treatments for preventing curve progression in idiopathic scoliosis.Methods/design:Patients: Previously untreated girls and boys with idiopathic scoliosis, 9 to 17 years of age with at least one year of remaining growth and a curve Cobb angle of 25–40 degrees will be included. A total of 135 participants will be randomly allocated in groups of 45 patients each to receive one of the three interventions.Interventions: All three groups will receive a physical activity prescription according to the World Health Organisation recommendations. One group will additionally wear a hyper-corrective night-time brace. One group will additionally perform postural scoliosis-specific exercises.Outcome: Participation in the study will last until the curve has progressed, or until cessation of skeletal growth. Outcome variables will be measured every 6 months. The primary outcome variable, failure of treatment, is defined as progression of the Cobb angle more than 6 degrees, compared to the primary x-ray, seen on two consecutive spinal standing x-rays taken with 6 months interval. Secondary outcome measures include the SRS-22r and EQ5D-Y quality of life questionnaires, the International Physical Activity Questionnaire (IPAQ) short form, and Cobb angle atend of the study.Discussion:This trial will evaluate which of the tested conservative treatment approaches that is the most effective for patients with adolescent idiopathic scoliosis.Trial registration: NCT01761305

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng
Idiopathic scoliosis; Treatment; Brace; Exercise

Biuppslag (personer, institutioner, konferenser, titlar ...)

Möller, HansKarolinska Institutet,Karolinska Institutet, Stockholm, Sweden; Karolinska University Hospital, Stockholm, Sweden (författare)
Gerdhem, PaulKarolinska Institutet,Karolinska Institutet, Stockholm, Sweden; Karolinska University Hospital, Stockholm, Sweden (författare)
Karolinska InstitutetKarolinska Institutet, Stockholm, Sweden; Karolinska University Hospital, Stockholm, Sweden; Bond University, Gold Coast, Australia (creator_code:org_t)

Sammanhörande titlar

Ingår i:BMC Musculoskeletal Disorders: BioMed Central141471-2474

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Av författaren/redakt...: Abbott, Allan; Möller, Hans; Gerdhem, Paul

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin

Artiklar i publikationen: BMC Musculoskele ...

Av lärosätet: Linköpings universitet; Karolinska Institutet

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