SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Tran Nhan)
 

Search: WFRF:(Tran Nhan) > Burden of Hospital ...

  • Phu, Vu DinhNatl Hosp Trop Dis, Intens Care Unit, Hanoi, Vietnam (author)

Burden of Hospital Acquired Infections and Antimicrobial Use in Vietnamese Adult Intensive Care Units

  • Article/chapterEnglish2016

Publisher, publication year, extent ...

  • 2016-01-29
  • PUBLIC LIBRARY SCIENCE,2016
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-125684
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-125684URI
  • https://doi.org/10.1371/journal.pone.0147544DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:132921832URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Background Vietnam is a lower middle-income country with no national surveillance system for hospital-acquired infections (HAIs). We assessed the prevalence of hospital-acquired infections and antimicrobial use in adult intensive care units (ICUs) across Vietnam. Methods Monthly repeated point prevalence surveys were systematically conducted to assess HAI prevalence and antimicrobial use in 15 adult ICUs across Vietnam. Adults admitted to participating ICUs before 08: 00 a.m. on the survey day were included. Results Among 3287 patients enrolled, the HAI prevalence was 29.5% (965/3266 patients, 21 missing). Pneumonia accounted for 79.4% (804/1012) of HAIs Most HAIs (84.5% [855/1012]) were acquired in the survey hospital with 42.5% (363/855) acquired prior to ICU admission and 57.5% (492/855) developed during ICU admission. In multivariate analysis, the strongest risk factors for HAI acquired in ICU were: intubation (OR 2.76), urinary catheter (OR 2.12), no involvement of a family member in patient care (OR 1.94), and surgery after admission (OR 1.66). 726 bacterial isolates were cultured from 622/1012 HAIs, most frequently Acinetobacter baumannii (177/726 [24.4%]), Pseudomonas aeruginosa (100/726 [13.8%]), and Klebsiella pneumoniae (84/726 [11.6%]), with carbapenem resistance rates of 89.2%, 55.7%, and 14.9% respectively. Antimicrobials were prescribed for 84.8% (2787/ 3287) patients, with 73.7% of patients receiving two or more. The most common antimicrobial groups were third generation cephalosporins, fluoroquinolones, and carbapenems (20.1%, 19.4%, and 14.1% of total antimicrobials, respectively). Conclusion A high prevalence of HAIs was observed, mainly caused by Gram-negative bacteria with high carbapenem resistance rates. This in combination with a high rate of antimicrobial use illustrates the urgent need to improve rational antimicrobial use and infection control efforts.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Wertheim, Heiman FLUniv Oxford, Clin Res Unit, Wellcome Trust Major Overseas Programme, Hanoi, Vietnam; Univ Oxford, Nuffield Dept Clin Med, Ctr Trop Med, Oxford OX1 2JD, England (author)
  • Larsson, MattiasKarolinska Institutet,Karolinska Institute, Sweden (author)
  • Nadjm, BehzadUniversity of Oxford, England (author)
  • Dinh, Quynh-DaoUniv Oxford, Clin Res Unit, Wellcome Trust Major Overseas Programme, Hanoi, Vietnam (author)
  • Nilsson, Lennart ELinköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten(Swepub:liu)lenni43 (author)
  • Rydell, UlfLinköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Hälsouniversitetet(Swepub:liu)ulfry79 (author)
  • Le, Tuyet Thi DiemBach Mai Hosp, Intens Care Unit, Hanoi, Vietnam (author)
  • Trinh, Son HongViet Duc Hosp, Board Directors, Hanoi, Vietnam (author)
  • Pham, Hung MinhSt Paul Hosp, Pharm, Hanoi, Vietnam (author)
  • Tran, Cang ThanhViet Tiep Hosp, Intens Care, Hai Phong, Vietnam (author)
  • Doan, Hanh Thi HongVietnam Sweden Uong Bi Hosp, Board Directors, Quang Ninh, Vietnam (author)
  • Tran, Nguyen ThuaHue Cent Gen Hosp, Dept Gen Internal Med & Geriatr, Hue, Vietnam (author)
  • Le, Nhan DucDa Nang Hosp, Board Directors, Da Nang, Vietnam (author)
  • Van Huynh, NhuanBinh Dinh Hosp, Infect Dept, Binh Dinh, Vietnam (author)
  • Tran, Thao PhuongKhanh Hoa Hosp, Intens Care Unit, Khanh Hoa, Vietnam (author)
  • Tran, Bao DucDak Lak Hosp, Planning Dept, Dak Lak, Vietnam (author)
  • Nguyen, Son TruongCho Ray Hosp, Board Directors, Ho Chi Minh City, Vietnam (author)
  • Pham, Thao Thi NgocCho Ray Hosp, Board Directors, Ho Chi Minh City, Vietnam (author)
  • Dang, Tam QuangCan Tho Cent Gen Hosptial, Board Directors, Can Tho, Vietnam (author)
  • Nguyen, Chau Van VinhHosp Trop Dis, Board Directors, Ho Chi Minh City, Vietnam,Natl Hosp Trop Dis, Board Directors, Hanoi, Vietnam (author)
  • Lam, Yen MinhHosp Trop Dis, Board Directors, Ho Chi Minh City, Vietnam (author)
  • Thwaites, GuyUniv Oxford, Nuffield Dept Clin Med, Ctr Trop Med, Oxford OX1 2JD, England; Univ Oxford, Clin Res Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam (author)
  • Van Nguyen, KinhNatl Hosp Trop Dis, Board Directors, Hanoi, Vietnam (author)
  • Hanberger, HåkanLinköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland(Swepub:liu)hakha84 (author)
  • Natl Hosp Trop Dis, Intens Care Unit, Hanoi, VietnamUniv Oxford, Clin Res Unit, Wellcome Trust Major Overseas Programme, Hanoi, Vietnam; Univ Oxford, Nuffield Dept Clin Med, Ctr Trop Med, Oxford OX1 2JD, England (creator_code:org_t)

Related titles

  • In:PLOS ONE: PUBLIC LIBRARY SCIENCE11:11932-6203

Internet link

Find in a library

  • PLOS ONE (Search for host publication in LIBRIS)

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view