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Vitamin D levels an...
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Johansson, PeterLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
(författare)
Vitamin D levels and depressive symptoms in patients with chronic heart failure
- Artikel/kapitelEngelska2016
Förlag, utgivningsår, omfång ...
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ELSEVIER IRELAND LTD,2016
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Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-126804
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-126804URI
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https://doi.org/10.1016/j.ijcard.2016.01.173DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Funding Agencies|Netherlands Heart Foundation [2000Z003]
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Background: Vitamin D (Vit D) is suggested to play a role in the regulation of physical function as well as in depression. Since, Vit D deficiency is common in patients with heart failure (HF), this study aims to explore if Vit D levels are associated with depressive symptoms and if this association is mediated by the patients physical function. Method: 506 HF patients (mean age 71, 38% women) were investigated. Depressive symptoms and physical function were measured with the Centre for Epidemiological Studies Depression Scale and the physical function scale from the RAND-36. Vit D was measured in blood samples Results: At baseline there was no relationship between depressive symptoms and Vit D levels. However, at 18 months follow-up 29% of patients with Vit D < 50 nmol/l at baseline had depressive symptoms compared 19% of those with Vit D levels >50 nmol/l (p < 0.05). Only in patients with Vit D < 50 nmol/l, Vit D correlated significantly to physical function and depressive symptoms (r = .29, p < 0.001 and r = .20, p < 0.01). In structural equation modelling an indirect association between Vit D and depressive symptoms was found, mediated by physical function (B = 0.20). This association was only found in patients with Vit D levels <50 nmol/l. Conclusion: In HF patients with Vit D < 50 nmol/l, Vit D is associated to depressive symptoms during follow-up and this association is mediated by physical function. This relationship is not found in patients with Vitamin D level >50 nmol/l. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Alehagen, UrbanLinköpings universitet,Medicinska fakulteten,Avdelningen för kardiovaskulär medicin,Region Östergötland, Kardiologiska kliniken US(Swepub:liu)urbal84
(författare)
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van der Wal, Martje H. L.Linköpings universitet,Medicinska fakulteten,Hälsa, Aktivitet, Vård (HAV),University of Groningen, Netherlands
(författare)
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Svensson, ErlandSwedish Def Research Agency, Linkoping, Sweden
(författare)
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Jaarsma, TinyLinköpings universitet,Avdelningen för omvårdnad,Medicinska fakulteten(Swepub:liu)tinja77
(författare)
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Linköpings universitetAvdelningen för kardiovaskulär medicin
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:International Journal of Cardiology: ELSEVIER IRELAND LTD207, s. 185-1890167-52731874-1754
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