Search: WFRF:(Klasson Anna) >
Synthesis and Chara...
Synthesis and Characterization of Tb3+-Doped Gd2O3 Nanocrystals : A Bifunctional Material with Combined Fluorescent Labeling and MRI Contrast Agent Properties
-
- Petoral, Rodrigo M (author)
- Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten
-
- Söderlind, Fredrik (author)
- Linköpings universitet,Institutionen för fysik, kemi och biologi,Tekniska högskolan
-
- Klasson, Anna (author)
- Östergötlands Läns Landsting,Linköpings universitet,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Medicinsk radiologi,Hälsouniversitetet,Röntgenkliniken i Linköping
-
show more...
-
- Suska, Anke (author)
- Linköpings universitet,Tillämpad Fysik,Tekniska fakulteten
-
- Fortin, Marc-André (author)
- Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten
-
- Abrikossova, Natalia (author)
- Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten
-
- Selegard, Linnea (author)
- Linköpings universitet,Sensorvetenskap och Molekylfysik,Tekniska högskolan
-
- Käll, Per-Olov (author)
- Linköpings universitet,Fysikalisk Kemi,Tekniska högskolan
-
- Engström, Maria (author)
- Östergötlands Läns Landsting,Linköpings universitet,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Medicinsk radiologi,Hälsouniversitetet,Röntgenkliniken i Linköping
-
- Uvdal, Kajsa (author)
- Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten
-
show less...
-
(creator_code:org_t)
- 2009-04-08
- 2009
- English.
-
In: The Journal of Physical Chemistry C. - : American Chemical Society (ACS). - 1932-7447 .- 1932-7455. ; 113:17, s. 6913-6920
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Ultrasmall gadolinium oxide nanoparticles doped with terbium ions were synthesized by the polyol route and characterized as a potentially bifunctional material with both fluorescent and magnetic contrast agent properties. The structural, optical, and magnetic properties of the organic-acid-capped and PEGylated Gd2O3:Tb3+ nanocrystals were studied by HR-TEM, XPS, EDX, IR, PL, and SQUID. The luminescent/fluorescent property of the particles is attributable to the Tb3+ ion located on the crystal lattice of the Gd2O3 host. The paramagnetic behavior of the particles is discussed. Pilot studies investigating the capability of the nanoparticles for fluorescent labeling of living cells and as a MRI contrast agent were also performed. Cells of two cell lines (THP-1 cells and fibroblasts) were incubated with the particles, and intracellular particle distribution was visualized by confocal microscopy. The MRI relaxivity of the PEGylated nanoparticles in water at low Gd concentration was assessed showing a higher T-1 relaxation rate compared to conventional Gd-DTPA chelates and comparable to that of undoped Gd2O3 nanoparticles.
Keyword
- NATURAL SCIENCES
- NATURVETENSKAP
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Petoral, Rodrigo ...
-
Söderlind, Fredr ...
-
Klasson, Anna
-
Suska, Anke
-
Fortin, Marc-And ...
-
Abrikossova, Nat ...
-
show more...
-
Selegard, Linnea
-
Käll, Per-Olov
-
Engström, Maria
-
Uvdal, Kajsa
-
show less...
- Articles in the publication
-
The Journal of P ...
- By the university
-
Linköping University