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Using big data from...
Using big data from health records from four countries to evaluate chronic disease outcomes : a study in 114 364 survivors of myocardial infarction
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- Rapsomaniki, Eleni (författare)
- Farr Institute of Health Informatics Research, University College London, London, UK
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- Thuresson, Marcus (författare)
- Statisticon AB, Uppsala, Sweden
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- Yang, Erru (författare)
- Retrospective Observational Studies, Evidera, Lexington, MA, USA
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- Blin, Patrick (författare)
- University of Bordeaux, Bordeaux, France
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- Hunt, Phillip (författare)
- Retrospective Observational Studies, Evidera, Lexington, MA, USA
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- Chung, Sheng-Chia (författare)
- Farr Institute of Health Informatics Research, University College London, London, UK
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- Stogiannis, Dimitris (författare)
- University of Athens, Athens, Greece
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- Pujades-Rodriguez, Mar (författare)
- Farr Institute of Health Informatics Research, University College London, London, UK
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- Timmis, Adam (författare)
- Farr Institute of Health Informatics Research, University College London, London, UK
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- Denaxas, Spiros C (författare)
- Farr Institute of Health Informatics Research, University College London, London, UK
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- Danchin, Nicolas (författare)
- Hopital Européen Georges Pompidou, Paris, France
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- Stokes, Michael (författare)
- Retrospective Observational Studies, Evidera, Lexington, MA, USA
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- Thomas-Delecourt, Florence (författare)
- Epidemiology, AstraZeneca Rueil-Malmaison, Rueil-Malmaison, France
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- Emmas, Cathy (författare)
- Astra Zeneca Luton, Luton, UK
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- Hasvold, Pål (författare)
- Medical Department, AstraZeneca Nordic-Baltic, Oslo, Norway
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- Jennings, Em (författare)
- Global Payer Evidence and Pricing, AstraZeneca R&D, Cambridge, UK
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- Johansson, Saga (författare)
- Global Medicines Development, AstraZeneca Gothenburg, Mo¨ lndal, Sweden
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- Cohen, David J (författare)
- Saint Luke’s Mid America Heart Institute, Kansas City, MO, USA
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- Jernberg, Tomas (författare)
- Karolinska Institutet
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- Moore, Nicholas (författare)
- University of Bordeaux, Bordeaux, France
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- Janzon, Magnus (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Medicinska fakulteten,Kardiologiska kliniken US,Avdelningen för kardiovaskulär medicin
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- Hemingway, Harry (författare)
- Farr Institute of Health Informatics Research, University College London, London, UK
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(creator_code:org_t)
- 2016-02-15
- 2016
- Engelska.
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Ingår i: European Heart Journal - Quality of Care and Clinical Outcomes. - : Oxford University Press. - 2058-5225 .- 2058-1742. ; 2:3, s. 172-183
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https://academic.oup...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Aims To assess the international validity of using hospital record data to compare long-term outcomes in heart attack survivors.Methods and results We used samples of national, ongoing, unselected record sources to assess three outcomes: cause death; a composite of myocardial infarction (MI), stroke, and all-cause death; and hospitalized bleeding. Patients aged 65 years and older entered the study 1 year following the most recent discharge for acute MI in 2002–11 [n = 54 841 (Sweden), 53 909 (USA), 4653 (England), and 961 (France)]. Across each of the four countries, we found consistent associations with 12 baseline prognostic factors and each of the three outcomes. In each country, we observed high 3-year crude cumulative risks of all-cause death (from 19.6% [England] to 30.2% [USA]); the composite of MI, stroke, or death [from 26.0% (France) to 36.2% (USA)]; and hospitalized bleeding [from 3.1% (France) to 5.3% (USA)]. After adjustments for baseline risk factors, risks were similar across all countries [relative risks (RRs) compared with Sweden not statistically significant], but higher in the USA for all-cause death [RR USA vs. Sweden, 1.14 (95% confidence interval 1.04–1.26)] and hospitalized bleeding [RR USA vs. Sweden, 1.54 (1.21–1.96)].Conclusion The validity of using hospital record data is supported by the consistency of estimates across four countries of a high adjusted risk of death, further MI, and stroke in the chronic phase after MI. The possibility that adjusted risks of mortality and bleeding are higher in the USA warrants further study.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Acute myocardial infarction
- Co-morbidities
- Healthcare systems
- International comparison
- Long-term outcomes
- EHR
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- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Rapsomaniki, Ele ...
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Thuresson, Marcu ...
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Yang, Erru
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Blin, Patrick
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Hunt, Phillip
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Chung, Sheng-Chi ...
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Stogiannis, Dimi ...
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Pujades-Rodrigue ...
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Timmis, Adam
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Denaxas, Spiros ...
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Danchin, Nicolas
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Stokes, Michael
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Thomas-Delecourt ...
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Emmas, Cathy
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Hasvold, Pål
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Jennings, Em
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Johansson, Saga
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Cohen, David J
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Jernberg, Tomas
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Moore, Nicholas
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Janzon, Magnus
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Hemingway, Harry
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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European Heart J ...
- Av lärosätet
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Linköpings universitet
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Karolinska Institutet