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  • Rådegran, GöranLund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund Hemodynamic Lab,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,Department of Clinical Sciences Lund, Cardiology, Lund University, Lund, Sweden; Haemodynamic Laboratory, the Section for Heart Failure and Valvular Disease, VO Heart and Lung Medicine, Skåne University Hospital, Lund, Sweden (author)

Characteristics and survival of adult Swedish PAH and CTEPH patients 2000-2014

  • Article/chapterEnglish2016

Publisher, publication year, extent ...

  • 2016-06-14
  • Taylor & Francis,2016
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-130206
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-130206URI
  • https://doi.org/10.1080/14017431.2016.1185532DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-300983URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-124526URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:133950294URI
  • https://lup.lub.lu.se/record/c1a1aec5-98c2-415a-94f6-7df649c190faURI
  • https://gup.ub.gu.se/publication/236120URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding agencies:  Actelion Pharmaceuticals Sweden AB; Bayer Health Care; Eli Lilly Sweden; Glaxo-SmithKline; Nordicinfu Care; Pfizer; SALAR (SKL); "ALF" foundations
  • OBJECTIVES: The Swedish Pulmonary Arterial Hypertension Register (SPAHR) is an open continuous register, including pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) patients from 2000 and onwards. We hereby launch the first data from SPAHR, defining baseline characteristics and survival of Swedish PAH and CTEPH patients.DESIGN: Incident PAH and CTEPH patients 2008-2014 from all seven Swedish PAH-centres were specifically reviewed.RESULTS: There were 457 PAH (median age: 67 years, 64% female) and 183 CTEPH (median age: 70 years, 50% female) patients, whereof 77 and 81%, respectively, were in functional class III-IV at diagnosis. Systemic hypertension, diabetes, ischaemic heart disease and atrial fibrillation were common comorbidities, particularly in those >65 years. One-, 3- and 5-year survival was 85%, 71% and 59% for PAH patients. Corresponding numbers for CTEPH patients with versus without pulmonary endarterectomy were 96%, 89% and 86% versus 91%, 75% and 69%, respectively. In 2014, the incidence of IPAH/HPAH, associated PAH and CTEPH was 5, 3 and 2 per million inhabitants and year, and the prevalence was 25, 24 and 19 per million inhabitants.CONCLUSION: The majority of the PAH and CTEPH patients were diagnosed at age >65 years, in functional class III-IV, and exhibiting several comorbidities. PAH survival in SPAHR was similar to other registers.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Kjellström, BarbroKarolinska Institute,Karolinska Institutet,Cardiology Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden (author)
  • Ekmehag, BjörnUppsala universitet,Vårdvetenskap,Univ Uppsala Hosp, Uppsala, Sweden.,Department of Public Health and Caring Science, Uppsala University and Uppsala University Hospital, Uppsala, Sweden(Swepub:lu)kard-bek (author)
  • Larsen, FlemmingKarolinska Institutet,Department of Molecular Medicine and Surgery, Section of Clinical Physiology, Karolinska Institute, Stockholm, Sweden; Department of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden (author)
  • Rundqvist, Bengt,1950Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xrunbe (author)
  • Berg Blomquist, SofiaUppsala University,Uppsala universitet,Kardiologi,Department of Medical Sciences Cardiology, Uppsala University, Uppsala, Sweden (author)
  • Gustafsson, CarolaGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine (author)
  • Hesselstrand, RogerLund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Clinical Sciences Lund, Rheumatology, Lund University, and the Rheumatology Clinic, Skåne University Hospital, Lund, Sweden(Swepub:lu)reum-rhe (author)
  • Karlsson, MonicaLinköping University,Region Östergötland, Kardiologiska kliniken US,Region Östergötland, Fysiologiska kliniken US(Swepub:lu)extLU-671 (author)
  • Kornhall, BjörnLund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Clinical Sciences Lund, Cardiology, Lund University, Lund, Sweden; Haemodynamic Laboratory, the Section for Heart Failure and Valvular Disease, VO Heart and Lung Medicine, Skåne University Hospital, Lund, Sweden(Swepub:lu)kard-bko (author)
  • Nisell, MagnusKarolinska Institutet,Department of Medicine, Karolinska Institute, Stockholm, Sweden; Clinic for Pulmonary Medicine, Karolinska University Hospital, Stockholm, Sweden (author)
  • Persson, LiselotteDepartment of Clinical Sciences Lund, Cardiology, Lund University, Lund, Sweden; Haemodynamic Laboratory, the Section for Heart Failure and Valvular Disease, VO Heart and Lung Medicine, Skåne University Hospital, Lund, Sweden,Lund Univ, Dept Clin Sci Lund, Cardiol, Lund, Sweden.;Skåne Univ Hosp, Haemodynam Lab, Sect Heart Failure & Valvular Dis, VO Heart & Lung Med, S-22185 Lund, Sweden. (author)
  • Ryftenius, HenrikDepartment of Medicine, Karolinska Institute, Stockholm, Sweden; Clinic for Pulmonary Medicine, Karolinska University Hospital, Stockholm, Sweden,Karolinska Inst, Dept Med, Stockholm, Sweden.;Karolinska Univ Hosp, Clin Pulm Med, Stockholm, Sweden. (author)
  • Selin, MariaUmeå University,Umeå universitet,Kardiologi,Department of Public Health and Clinical Medicine, Cardiology and the Heart Centre, Umeå University, Umeå, Sweden (author)
  • Ullman, BengtKarolinska Institute,Department of Cardiology, Karolinska Institute, Stockholm, Sweden; Department of Cardiology, Södersjukhuset, Sweden, Stockholm (author)
  • Wall, KentDepartment of Clinical Physiology, Örebro University, and Örebro University Hospital, Örebro, Sweden,Univ Örebro, Dept Clin Physiol, Örebro, Sweden.;Örebro Univ Hosp, Örebro, Sweden. (author)
  • Wikström, GerhardUppsala University,Uppsala universitet,Kardiologi,Department of Medical Sciences Cardiology, Uppsala University, Uppsala, Sweden(Swepub:uu)gewik021 (author)
  • Willehadson, MariaUppsala University,Uppsala universitet,Kardiologi,Department of Medical Sciences Cardiology, Uppsala University, Uppsala, Sweden (author)
  • Jansson, KjellLinköping University,Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Fysiologiska kliniken US,Region Östergötland, Kardiologiska kliniken US,Linköping Univ, Inst Med & Hlth Sci, Dept Cardiol, Linköping, Sweden.;Linköping Univ, Inst Med & Hlth Sci, Dept Clin Physiol, Linköping, Sweden.(Swepub:liu)kjeja02 (author)
  • Söderberg, StefanUmeå universitet,Kardiologi,Department of Medicine, Karolinska Institute, Stockholm, Sweden; Clinic for Pulmonary Medicine, Karolinska University Hospital, Stockholm, Sweden(Swepub:umu)stso0001 (author)
  • KardiologiSektion II (creator_code:org_t)

Related titles

  • In:Scandinavian Cardiovascular Journal: Taylor & Francis50:4, s. 243-2501401-74311651-2006

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