Search: (WFRF:(Camm John)) pers:(Verhamme Peter)
> (2016) >
Managing reversal o...
-
Ageno, WalterUniversity of Insubria, Italy
(author)
Managing reversal of direct oral anticoagulants in emergency situations Anticoagulation Education Task Force White Paper
- Article/chapterEnglish2016
Publisher, publication year, extent ...
-
SCHATTAUER GMBH-VERLAG MEDIZIN NATURWISSENSCHAFTEN,2016
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:liu-133256
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-133256URI
-
https://doi.org/10.1160/TH16-05-0363DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Funding Agencies|Boehringer Ingelheim
-
Anticoagulation is the cornerstone of prevention and treatment of venous thromboembolism (VTE) and stroke prevention in patients with atrial fibrillation (AF). However, the mechanisms by which anticoagulants confer therapeutic benefit also increase the risk of bleeding. As such, reversal strategies are critical. Until recently, the direct oral anticoagulants (DOACs) dabigatran, rivaroxaban, apixaban, and edoxaban lacked a specific reversal agent. This report is based on findings from the Anticoagulation Education Task Force, which brought together patient groups and professionals representing different medical specialties with an interest in patient safety and expertise in AF, VTE, stroke, anticoagulation, and reversal agents, to discuss the current status of anticoagulation reversal and fundamental changes in management of bleeding associated with DOACs occasioned by the approval of idarucizumab, a specific reversal agent for dabigatran, as well as recent clinical data on specific reversal agents for factor Xa inhibitors. Recommendations are given for when there is a definite need for a reversal agent (e.g. in cases of life-threatening bleeding, bleeding into a closed space or organ, persistent bleeding despite local haemostatic measures, and need for urgent interventions and/or interventions that carry a high risk for bleeding), when reversal agents may be helpful, and when a reversal agent is generally not needed. Key stakeholders who require 24-7/around-the-clock access to these agents vary among hospitals; however, from a practical perspective the emergency department is recommended as an appropriate location for these agents. Clearly, the advent of new agents requires standardised protocols for treating bleeding on an institutional level.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Buller, Harry R.Academic Medical Centre, Netherlands
(author)
-
Falanga, AnnaHospital Papa Giovanni XXIII, Italy; Hospital Papa Giovanni XXIII, Italy
(author)
-
Hacke, WernerHeidelberg University, Germany
(author)
-
Hendriks, JeroenLinköpings universitet,Avdelningen för omvårdnad,Medicinska fakulteten,University of Adelaide, Australia(Swepub:liu)jerhe83
(author)
-
Lobban, TrudieArrhythmia Alliance and AF Assoc, England
(author)
-
Merino, JoseUniversity of La Paz, Spain
(author)
-
Milojevic, Ivan S.Gen Hospital Cuprija, Serbia
(author)
-
Moya, FranciscoVithas Xanit Int Hospital, Spain
(author)
-
Bart van der Worp, H.University of Medical Centre Utrecht, Netherlands
(author)
-
Randall, GarySAFE, England
(author)
-
Tsioufis, KonstantinosUniversity of Athens, Greece
(author)
-
Verhamme, PeterUniversity of Leuven, Belgium
(author)
-
John Camm, A.St Georges University of London, England; Imperial Coll, England
(author)
-
University of Insubria, ItalyAcademic Medical Centre, Netherlands
(creator_code:org_t)
Related titles
-
In:Thrombosis and Haemostasis: SCHATTAUER GMBH-VERLAG MEDIZIN NATURWISSENSCHAFTEN116:6, s. 1003-10100340-62452567-689X
Internet link
Find in a library
To the university's database
- By the author/editor
-
Ageno, Walter
-
Buller, Harry R.
-
Falanga, Anna
-
Hacke, Werner
-
Hendriks, Jeroen
-
Lobban, Trudie
-
show more...
-
Merino, Jose
-
Milojevic, Ivan ...
-
Moya, Francisco
-
Bart van der Wor ...
-
Randall, Gary
-
Tsioufis, Konsta ...
-
Verhamme, Peter
-
John Camm, A.
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cardiac and Card ...
- Articles in the publication
-
Thrombosis and H ...
- By the university
-
Linköping University