A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.

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Semb, GunvorDivision of Dentistry, University of Manchester , Manchester , UK; Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway; Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway. (author)

A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.

Article/chapterEnglish2017

Publisher, publication year, extent ...

Taylor & Francis,2017
printrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:liu-135511
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-135511URI
https://doi.org/10.1080/2000656X.2016.1263202DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:135262465URI
https://gup.ub.gu.se/publication/250636URI

Supplementary language notes

Language:English
Summary in:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Funding agencies: University of Manchester; University Hospital Rikshospitalet; Statped sorost, Oslo; European Commission Biomed II Programme; European Commission Framework V Programme; Swedish Research Council for Health, Working Life and Welfare [2011-1443]
BACKGROUND AND AIMS: Longstanding uncertainty surrounds the selection of surgical protocols for the closure of unilateral cleft lip and palate, and randomised trials have only rarely been performed. This paper is an introduction to three randomised trials of primary surgery for children born with complete unilateral cleft lip and palate (UCLP). It presents the protocol developed for the trials in CONSORT format, and describes the management structure that was developed to achieve the long-term engagement and commitment required to complete the project.METHOD: Ten established national or regional cleft centres participated. Lip and soft palate closure at 3-4 months, and hard palate closure at 12 months served as a common method in each trial. Trial 1 compared this with hard palate closure at 36 months. Trial 2 compared it with lip closure at 3-4 months and hard and soft palate closure at 12 months. Trial 3 compared it with lip and hard palate closure at 3-4 months and soft palate closure at 12 months. The primary outcomes were speech and dentofacial development, with a series of perioperative and longer-term secondary outcomes.RESULTS: Recruitment of 448 infants took place over a 9-year period, with 99.8% subsequent retention at 5 years.CONCLUSION: The series of reports that follow this introductory paper include comparisons at age 5 of surgical outcomes, speech outcomes, measures of dentofacial development and appearance, and parental satisfaction. The outcomes recorded and the numbers analysed for each outcome and time point are described in the series.TRIAL REGISTRATION: ISRCTN29932826.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kirurgi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Surgery hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Oto-rhino-laryngologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Otorhinolaryngology hsv//eng
Scandcleft Project
multicentre study
randomised controlled trials
surgery for unilateral complete cleft lip and palate

Added entries (persons, corporate bodies, meetings, titles ...)

Enemark, HansCleft Palate Center , Aarhus , Denmark (author)
Friede, Hans,1938Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology(Swepub:gu)xfrieh (author)
Paulin, GunnarRegion Östergötland, Käkkliniken US(Swepub:liu)gunpa61 (author)
Lilja, Jan,1942Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery(Swepub:gu)xliljj (author)
Rautio, JormaCleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland (author)
Andersen, MikaelCopenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark (author)
Åbyholm, FrankDepartment of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway (author)
Lohmander, AnetteKarolinska Institutet,Division of Speech and Language Pathology , Karolinska Institute, and Karolinska University Hospital , Stockholm , Sweden (author)
Shaw, WilliamDivision of Dentistry, University of Manchester , Manchester , UK (author)
Mølsted, KirstenCopenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark (author)
Heliövaara, ArjaCleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland (author)
Bolund, StigCopenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark (author)
Hukki, JyriCleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland (author)
Vindenes, HallvardCentre for Cleft Lip and Palate, Bergen University Hospital Haukeland , Bergen , Norway (author)
Davenport, PeterGreater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK (author)
Arctander, KjartanDepartment of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway (author)
Larson, OlaStockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden (author)
Berggren, AndersRegion Östergötland, Hand- och plastikkirurgiska kliniken US(Swepub:liu)andbe26 (author)
Whitby, DavidGreater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK (author)
Leonard, AlanThe Royal Hospital for Sick Children , Belfast , N. Ireland (author)
Neovius, ErikStockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden (author)
Elander, Anna,1955Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery(Swepub:gu)xelaan (author)
Willadsen, ElisabethDepartment of Nordic Studies and Linguistics , University of Copenhagen , Denmark (author)
Bannister, R. PatriciaGreater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK (author)
Bradbury, EileenPrivate Practitioner , Manchester , UK (author)
Henningsson, GunillaStockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden (author)
Persson, Christina,1959Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för hälsa och rehabilitering,Institute of Neuroscience and Physiology, Department of Health and Rehabilitation(Swepub:gu)xperch (author)
Eyres, PhilipDivision of Dentistry, University of Manchester , Manchester , UK (author)
Emborg, BeritCleft Palate Center , Aarhus , Denmark (author)
Kisling-Møller, MiaDivision of Dentistry, University of Manchester , Manchester , UK (author)
Küseler, AnneliseDivision of Dentistry, University of Manchester , Manchester , UK (author)
Granhof Black, BirtheDivision of Dentistry, University of Manchester , Manchester , UK (author)
Schöps, AntjeCopenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark (author)
Bau, AnjaCopenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark (author)
Boers, MariaCopenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark (author)
Søgaard Andersen, HeleneCopenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark (author)
Jeppesen, KarinCopenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark (author)
Marxen, DorteCopenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark (author)
Paaso, MarjukkaCleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland (author)
Hölttä, ElinaCleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland (author)
Alaluusua, SuviCleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland (author)
Turunen, LeenaCleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland (author)
Humerinta, KirstiCleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland (author)
Elfving-Little, UllaCleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland (author)
Tørdal, Inger BeateDepartment of Speech and Language Disorders , Statped sørøst , Oslo , Norway (author)
Kjøll, LillianDepartment of Speech and Language Disorders , Statped sørøst , Oslo , Norway (author)
Aukner, RagnhildDepartment of Speech and Language Disorders , Statped sørøst , Oslo , Norway (author)
Hide, ØydisDepartment of Speech and Language Disorders , Statped sørøst , Oslo , Norway (author)
Feragen, Kristin BillaudDepartment of Speech and Language Disorders , Statped sørøst , Oslo , Norway (author)
Rønning, ElisabethDepartment of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway (author)
Skaare, PålDepartment of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway (author)
Brinck, EliDepartment of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway (author)
Semmingsen, Ann-MagrittDepartment of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway (author)
Lindberg, NinaDepartment of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway (author)
Bowden, MelanieGreater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK (author)
Davies, JulieGreater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK (author)
Mooney, JeanetteGreater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK (author)
Bellardie, HaydnGreater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK (author)
Schofield, NinaGreater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK (author)
Nyberg, JillKarolinska Institutet,Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden (author)
Lundberg, MariaStockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden (author)
Linder-Aronson Karsten, AgnetaStockholm Craniofacial Team, Department of Dental Medicine , Karolinska Institute , Stockholm , Sweden (author)
Larson, MargaretaEastman Institute, Stockholms Läns Landsting , Stockholm , Sweden (author)
Holmefjord, AndersStatped vest , Bergen , Norway (author)
Reisæter, SigvorStatped vest , Bergen , Norway (author)
Pedersen, Nina-HelenStatped vest , Bergen , Norway (author)
Rasmussen, ThereseStatped vest , Bergen , Norway (author)
Tindlund, RolfDental School, University of Bergen , Bergen , Norway (author)
Sæle, PaulOral Health Center of Expertise/Western Norway , Bergen , Norway (author)
Blomhoff, ReidunnCentre for Cleft Lip and Palate, Bergen University Hospital Haukeland , Bergen , Norway (author)
Jacobsen, GryCentre for Cleft Lip and Palate, Bergen University Hospital Haukeland , Bergen , Norway (author)
Havstam, ChristinaDivision for Speech and Language Pathology , Sahlgrenska University Hospital , Gothenburg , Sweden (author)
Rizell, Sara,1963Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology(Swepub:gu)xrizsa (author)
Enochson, LarsGothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine(Swepub:gu)xenola (author)
Hagberg, Catharina,1949Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology(Swepub:gu)xhagbc (author)
Najar Chalien, MidiaGothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology (author)
Paganini, Anna,1979Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery(Swepub:gu)xpagan (author)
Lundeborg, Inger,1956-Linköpings universitet,Avdelningen för Logopedi, Audiologi och Otorhinolaryngologi,Medicinska fakulteten(Swepub:liu)inglu20 (author)
Marcusson, Agneta,1956-Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Käkkliniken US(Swepub:liu)agnma12 (author)
Mjönes, Anna-BrittaRegion Östergötland, Öron- näsa- och halskliniken US(Swepub:liu)annmj11 (author)
Gustavsson, AnnicaRegion Östergötland, Käkkliniken US (author)
Hayden, ChristineThe Royal Hospital for Sick Children , Belfast , N. Ireland (author)
McAleer, EilishThe Royal Hospital for Sick Children , Belfast , N. Ireland (author)
Slevan, EmmaThe Royal Hospital for Sick Children , Belfast , N. Ireland (author)
Gregg, TerryThe Royal Hospital for Sick Children , Belfast , N. Ireland (author)
Worthington, HelenDivision of Dentistry, University of Manchester , Manchester , UK (author)
Hide, O (author)
Saele, P (author)
Division of Dentistry, University of Manchester , Manchester , UK; Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway; Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway.Cleft Palate Center , Aarhus , Denmark (creator_code:org_t)

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In:Journal of Plastic Surgery and Hand Surgery: Taylor & Francis51:1, s. 2-132000-656X2000-6764

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Surgery

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Otorhinolaryngol ...

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By the university: Linköping University; Karolinska Institutet; University of Gothenburg

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