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A Scandcleft random...
A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
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- Semb, Gunvor (author)
- Division of Dentistry, University of Manchester , Manchester , UK; Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway; Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway.
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- Enemark, Hans (author)
- Cleft Palate Center , Aarhus , Denmark
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- Friede, Hans, 1938 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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show more...
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- Paulin, Gunnar (author)
- Region Östergötland, Käkkliniken US
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- Lilja, Jan, 1942 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery
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- Rautio, Jorma (author)
- Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland
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- Andersen, Mikael (author)
- Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark
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- Åbyholm, Frank (author)
- Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway
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- Lohmander, Anette (author)
- Karolinska Institutet,Division of Speech and Language Pathology , Karolinska Institute, and Karolinska University Hospital , Stockholm , Sweden
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- Shaw, William (author)
- Division of Dentistry, University of Manchester , Manchester , UK
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- Mølsted, Kirsten (author)
- Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark
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- Heliövaara, Arja (author)
- Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland
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- Bolund, Stig (author)
- Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark
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- Hukki, Jyri (author)
- Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland
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- Vindenes, Hallvard (author)
- Centre for Cleft Lip and Palate, Bergen University Hospital Haukeland , Bergen , Norway
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- Davenport, Peter (author)
- Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK
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- Arctander, Kjartan (author)
- Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway
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- Larson, Ola (author)
- Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden
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- Berggren, Anders (author)
- Region Östergötland, Hand- och plastikkirurgiska kliniken US
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- Whitby, David (author)
- Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK
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- Leonard, Alan (author)
- The Royal Hospital for Sick Children , Belfast , N. Ireland
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- Neovius, Erik (author)
- Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden
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- Elander, Anna, 1955 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery
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- Willadsen, Elisabeth (author)
- Department of Nordic Studies and Linguistics , University of Copenhagen , Denmark
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- Bannister, R. Patricia (author)
- Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK
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- Bradbury, Eileen (author)
- Private Practitioner , Manchester , UK
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- Henningsson, Gunilla (author)
- Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden
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- Persson, Christina, 1959 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för hälsa och rehabilitering,Institute of Neuroscience and Physiology, Department of Health and Rehabilitation
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- Eyres, Philip (author)
- Division of Dentistry, University of Manchester , Manchester , UK
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- Emborg, Berit (author)
- Cleft Palate Center , Aarhus , Denmark
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- Kisling-Møller, Mia (author)
- Division of Dentistry, University of Manchester , Manchester , UK
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- Küseler, Annelise (author)
- Division of Dentistry, University of Manchester , Manchester , UK
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- Granhof Black, Birthe (author)
- Division of Dentistry, University of Manchester , Manchester , UK
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- Schöps, Antje (author)
- Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark
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- Bau, Anja (author)
- Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark
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- Boers, Maria (author)
- Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark
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- Søgaard Andersen, Helene (author)
- Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark
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- Jeppesen, Karin (author)
- Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark
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- Marxen, Dorte (author)
- Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark
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- Paaso, Marjukka (author)
- Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland
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- Hölttä, Elina (author)
- Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland
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- Alaluusua, Suvi (author)
- Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland
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- Turunen, Leena (author)
- Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland
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- Humerinta, Kirsti (author)
- Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland
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- Elfving-Little, Ulla (author)
- Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland
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- Tørdal, Inger Beate (author)
- Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway
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- Kjøll, Lillian (author)
- Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway
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- Aukner, Ragnhild (author)
- Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway
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- Hide, Øydis (author)
- Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway
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- Feragen, Kristin Billaud (author)
- Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway
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- Rønning, Elisabeth (author)
- Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway
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- Skaare, Pål (author)
- Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway
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- Brinck, Eli (author)
- Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway
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- Semmingsen, Ann-Magritt (author)
- Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway
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- Lindberg, Nina (author)
- Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway
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- Bowden, Melanie (author)
- Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK
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- Davies, Julie (author)
- Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK
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- Mooney, Jeanette (author)
- Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK
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- Bellardie, Haydn (author)
- Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK
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- Schofield, Nina (author)
- Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK
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- Nyberg, Jill (author)
- Karolinska Institutet,Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden
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- Lundberg, Maria (author)
- Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden
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- Linder-Aronson Karsten, Agneta (author)
- Stockholm Craniofacial Team, Department of Dental Medicine , Karolinska Institute , Stockholm , Sweden
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- Larson, Margareta (author)
- Eastman Institute, Stockholms Läns Landsting , Stockholm , Sweden
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- Holmefjord, Anders (author)
- Statped vest , Bergen , Norway
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- Reisæter, Sigvor (author)
- Statped vest , Bergen , Norway
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- Pedersen, Nina-Helen (author)
- Statped vest , Bergen , Norway
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- Rasmussen, Therese (author)
- Statped vest , Bergen , Norway
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- Tindlund, Rolf (author)
- Dental School, University of Bergen , Bergen , Norway
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- Sæle, Paul (author)
- Oral Health Center of Expertise/Western Norway , Bergen , Norway
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- Blomhoff, Reidunn (author)
- Centre for Cleft Lip and Palate, Bergen University Hospital Haukeland , Bergen , Norway
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- Jacobsen, Gry (author)
- Centre for Cleft Lip and Palate, Bergen University Hospital Haukeland , Bergen , Norway
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- Havstam, Christina (author)
- Division for Speech and Language Pathology , Sahlgrenska University Hospital , Gothenburg , Sweden
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- Rizell, Sara, 1963 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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- Enochson, Lars (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine
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- Hagberg, Catharina, 1949 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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- Najar Chalien, Midia (author)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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- Paganini, Anna, 1979 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery
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- Lundeborg, Inger, 1956- (author)
- Linköpings universitet,Avdelningen för Logopedi, Audiologi och Otorhinolaryngologi,Medicinska fakulteten
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- Marcusson, Agneta, 1956- (author)
- Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Käkkliniken US
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- Mjönes, Anna-Britta (author)
- Region Östergötland, Öron- näsa- och halskliniken US
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- Gustavsson, Annica (author)
- Region Östergötland, Käkkliniken US
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- Hayden, Christine (author)
- The Royal Hospital for Sick Children , Belfast , N. Ireland
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- McAleer, Eilish (author)
- The Royal Hospital for Sick Children , Belfast , N. Ireland
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- Slevan, Emma (author)
- The Royal Hospital for Sick Children , Belfast , N. Ireland
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- Gregg, Terry (author)
- The Royal Hospital for Sick Children , Belfast , N. Ireland
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- Worthington, Helen (author)
- Division of Dentistry, University of Manchester , Manchester , UK
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Hide, O (author)
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Saele, P (author)
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Division of Dentistry, University of Manchester , Manchester , UK; Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway; Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway Cleft Palate Center , Aarhus , Denmark (creator_code:org_t)
- Taylor & Francis, 2017
- 2017
- English.
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In: Journal of Plastic Surgery and Hand Surgery. - : Taylor & Francis. - 2000-656X .- 2000-6764. ; 51:1, s. 2-13
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://gup.ub.gu.se...
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Abstract
Subject headings
Close
- BACKGROUND AND AIMS: Longstanding uncertainty surrounds the selection of surgical protocols for the closure of unilateral cleft lip and palate, and randomised trials have only rarely been performed. This paper is an introduction to three randomised trials of primary surgery for children born with complete unilateral cleft lip and palate (UCLP). It presents the protocol developed for the trials in CONSORT format, and describes the management structure that was developed to achieve the long-term engagement and commitment required to complete the project.METHOD: Ten established national or regional cleft centres participated. Lip and soft palate closure at 3-4 months, and hard palate closure at 12 months served as a common method in each trial. Trial 1 compared this with hard palate closure at 36 months. Trial 2 compared it with lip closure at 3-4 months and hard and soft palate closure at 12 months. Trial 3 compared it with lip and hard palate closure at 3-4 months and soft palate closure at 12 months. The primary outcomes were speech and dentofacial development, with a series of perioperative and longer-term secondary outcomes.RESULTS: Recruitment of 448 infants took place over a 9-year period, with 99.8% subsequent retention at 5 years.CONCLUSION: The series of reports that follow this introductory paper include comparisons at age 5 of surgical outcomes, speech outcomes, measures of dentofacial development and appearance, and parental satisfaction. The outcomes recorded and the numbers analysed for each outcome and time point are described in the series.TRIAL REGISTRATION: ISRCTN29932826.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oto-rhino-laryngologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Otorhinolaryngology (hsv//eng)
Keyword
- Scandcleft Project
- multicentre study
- randomised controlled trials
- surgery for unilateral complete cleft lip and palate
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Semb, Gunvor
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Enemark, Hans
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Friede, Hans, 19 ...
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Paulin, Gunnar
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Lilja, Jan, 1942
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Rautio, Jorma
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show more...
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Andersen, Mikael
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Åbyholm, Frank
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Lohmander, Anett ...
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Shaw, William
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Mølsted, Kirsten
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Heliövaara, Arja
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Bolund, Stig
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Hukki, Jyri
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Vindenes, Hallva ...
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Davenport, Peter
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Arctander, Kjart ...
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Larson, Ola
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Berggren, Anders
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Whitby, David
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Leonard, Alan
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Neovius, Erik
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Elander, Anna, 1 ...
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Willadsen, Elisa ...
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Bannister, R. Pa ...
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Bradbury, Eileen
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Henningsson, Gun ...
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Persson, Christi ...
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Eyres, Philip
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Emborg, Berit
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Kisling-Møller, ...
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Küseler, Annelis ...
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Granhof Black, B ...
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Schöps, Antje
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Bau, Anja
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Boers, Maria
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Søgaard Andersen ...
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Jeppesen, Karin
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Marxen, Dorte
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Paaso, Marjukka
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Hölttä, Elina
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Alaluusua, Suvi
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Turunen, Leena
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Humerinta, Kirst ...
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Elfving-Little, ...
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Tørdal, Inger Be ...
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Kjøll, Lillian
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Aukner, Ragnhild
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Hide, Øydis
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Feragen, Kristin ...
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Rønning, Elisabe ...
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Skaare, Pål
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Brinck, Eli
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Semmingsen, Ann- ...
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Lindberg, Nina
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Bowden, Melanie
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Davies, Julie
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Mooney, Jeanette
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Bellardie, Haydn
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Schofield, Nina
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Nyberg, Jill
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Lundberg, Maria
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Linder-Aronson K ...
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Larson, Margaret ...
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Holmefjord, Ande ...
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Reisæter, Sigvor
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Pedersen, Nina-H ...
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Rasmussen, There ...
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Tindlund, Rolf
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Sæle, Paul
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Blomhoff, Reidun ...
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Jacobsen, Gry
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Havstam, Christi ...
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Rizell, Sara, 19 ...
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Enochson, Lars
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Hagberg, Cathari ...
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Najar Chalien, M ...
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Paganini, Anna, ...
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Lundeborg, Inger ...
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Marcusson, Agnet ...
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Mjönes, Anna-Bri ...
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Gustavsson, Anni ...
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Hayden, Christin ...
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McAleer, Eilish
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Slevan, Emma
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Gregg, Terry
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Worthington, Hel ...
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Hide, O
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Saele, P
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Otorhinolaryngol ...
- Articles in the publication
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Journal of Plast ...
- By the university
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Linköping University
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Karolinska Institutet
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University of Gothenburg