Sökning: WFRF:(Bolling Sternevald Elisabeth) >
Gastro-oesophageal ...
Gastro-oesophageal reflux symptoms and health-related quality of life in the adult general population--the Kalixanda study
-
- Ronkainen, J. (författare)
- Karolinska Institutet
-
- Aro, P. (författare)
- Center for Family Medicine, Karolinska Institutet, Stockholm, Sweden
-
- Storskrubb, T. (författare)
- Center for Family Medicine, Karolinska Institutet, Stockholm, Sweden
-
visa fler...
-
- Lind, T. (författare)
- Astra Zeneca R&D, Mölndal, Sweden
-
- Bolling-Sternevald, Elisabeth (författare)
- Karolinska Institutet
-
- Junghard, O. (författare)
- Astra Zeneca R&D, Mölndal, Sweden
-
- Talley, N.J. (författare)
- Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA
-
- Agréus, L. (författare)
- Karolinska Institutet
-
visa färre...
-
(creator_code:org_t)
- Wiley, 2006
- 2006
- Engelska.
-
Ingår i: Alimentary Pharmacology and Therapeutics. - : Wiley. - 0269-2813 .- 1365-2036. ; 23:12, s. 1725-1733
- Relaterad länk:
-
http://urn.kb.se/res...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- Background The impact of gastro-oesophageal reflux symptoms on health-related quality of life in the general population is poorly characterized. Aim To identify the frequency of troublesome reflux symptoms associated with impaired health-related quality of life in the general population. Methods A representative random sample of 3000 adult inhabitants of northern Sweden was surveyed using the validated Abdominal Symptom Questionnaire (response rate 74%). In total, 1001 random responders were endoscoped and assessed using the Short Form-36 Health Survey. Results Complete data were obtained for 999 subjects: 6% reported reflux symptoms (heartburn and/or regurgitation) daily, 14% weekly and 20% less than weekly during the previous 3 months. Compared with no reflux symptoms, a clinically relevant impairment of health-related quality of life (≥5 points and P < 0.05) was seen in all eight Short Form-36 dimensions for daily symptoms, in five dimensions for weekly symptoms and in one dimension for less than weekly symptoms. There were no meaningful differences in Short Form-36 scores between subjects with and without oesophagitis. Conclusions Most aspects of health-related quality of life were impaired in individuals with daily or weekly reflux symptoms. Troublesome reflux symptoms at least weekly may identify gastro-oesophageal reflux disease.
Nyckelord
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas